Adalat and Desyrel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adalat (nifedipine) and Desyrel (trazodone hydrochloride). Common drug interactions include dizziness among females and loss of consciousness among males.

The phase IV clinical study analyzes what interactions people have when they take Adalat and Desyrel. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Adalat?

Adalat has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 20,940 Adalat users. Check the latest studies of Adalat.

What is Desyrel?

Desyrel has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 6,595 Desyrel users. Check the latest studies of Desyrel.

On Jul, 15, 2026

39 people who take Adalat and Desyrel together, and have interactions are studied.

What are the common drug interactions of Adalat and Desyrel, by gender? *:

female:

Dizziness
Genital pruritus female (itching in vagina)
Impaired healing
Injury
Muscle cramp (painful sensation caused by muscle contraction)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tongue discolouration (colour change of tongue)
Vaginal burning sensation
Hypotension (abnormally low blood pressure)
Abdominal pain

male:

Loss of consciousness
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Pulmonary infarction (death of a small area of lung)
Speech disorder
Urine output increased
Angina pectoris (chest pain due to ischemia of the heart muscle)
Blood pressure decreased
Carotid artery occlusion (artery blockage)
Cerebral infarction (less blood supply to brain resulting tissue damage)

What are the common drug interactions of Adalat and Desyrel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthma
Blood pressure fluctuation
Fibromyalgia (a long-term condition which causes pain all over the body)
Gait disturbance
Intervertebral disc degeneration (spinal disc degeneration)
Malaise (a feeling of general discomfort or uneasiness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Nausea (feeling of having an urge to vomit)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

40-49:

Adverse event
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain
Difficulty in walking
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dysarthria (speech disorder)
Dysstasia (difficulty in standing)

50-59:

Complications of transplanted kidney
Cytomegalovirus colitis (an inflammation of the colon from virus)
Cytomegalovirus infection
Death
Fluid overload (too much fluid in the blood)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Incision site cellulitis (spreading bacterial skin infection at incision site)
Incision site erythema (redness of the skin at incision site)
Incision site pain
Lactic acidosis (low ph in body tissues)

60+:

Anxiety
Loss of consciousness
Deformity (disfigurement)
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Emotional distress
Fatigue (feeling of tiredness)
Hypokalaemia (low potassium)
Hypotension (abnormally low blood pressure)
Infection

What are the existing conditions these people have? *

Pain: 6 people, 15.38%
Hiv Infection: 4 people, 10.26%
Depression: 4 people, 10.26%
Asthma: 3 people, 7.69%
Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 2 people, 5.13%
Gastric Cancer (stomach cancer): 2 people, 5.13%
Diabetes: 2 people, 5.13%
Constipation: 2 people, 5.13%
Cachexia (loss of weight): 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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