Adcal and Spiriva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adcal (calcium carbonate) and Spiriva (tiotropium bromide monohydrate). Common drug interactions include fall among females and frequent bowel movements among males.

The phase IV clinical study analyzes what interactions people have when they take Adcal and Spiriva. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Adcal?

Adcal has active ingredients of calcium carbonate. eHealthMe is studying from 4,844 Adcal users. Check the latest studies of Adcal.

What is Spiriva?

Spiriva has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 156,666 Spiriva users. Check the latest studies of Spiriva.

On Aug, 01, 2026

93 people who take Adcal and Spiriva together, and have interactions are studied.

What are the common drug interactions of Adcal and Spiriva, by gender? *:

female:

Fall
Lower respiratory tract infection
Anaemia (lack of blood)
Pneumonia
Electrocardiogram qt prolonged
Alopecia (absence of hair from areas of the body)
Back pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Death
Confusional state

male:

Frequent bowel movements
Haematochezia (passage of stools containing blood)
Dysphonia (speech disorder attributable to a disorder of phonation)
Ear infection fungal
Fatigue (feeling of tiredness)
Fungal skin infection
Oral fungal infection
Oropharyngeal pain
Asthenia (weakness)
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Adcal and Spiriva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anxiety
Dry mouth
Insomnia (sleeplessness)
Mania (a state of abnormally elevated or irritable mood)
Mood altered (changes in mood)

40-49:

Anxiety
Claustrophobia (fear of having no escape and being closed in small spaces)
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Dry throat
Dysphagia (a condition in which swallowing is difficult or painful)
Dysphonia (speech disorder attributable to a disorder of phonation)
Ear infection fungal
Fatigue (feeling of tiredness)
Fungal skin infection

50-59:

Dyspnoea (difficult or laboured respiration)
Wheezing (a high-pitched whistling sound made while you breath)
Nausea (feeling of having an urge to vomit)
Decreased appetite
Dyspepsia (indigestion)
Flatulence (flatus expelled through the anus)
Headache (pain in head)
Lower respiratory tract infection
Postmenopausal haemorrhage (post-menopausal bleeding)
Urticaria (rash of round, red welts on the skin that itch intensely)

60+:

Frequent bowel movements
Haematochezia (passage of stools containing blood)
Nausea (feeling of having an urge to vomit)
Asthenia (weakness)
Electrocardiogram qt prolonged
Vomiting
Pain in extremity
Tendon rupture (tear of tendon)
Tendonitis (a condition that causes pain and swelling of tendons)
Joint swelling

What are the existing conditions these people have? *

Stable Angina (a constant chest pain): 24 people, 25.81%
Gastric Ulcer (stomach ulcer): 24 people, 25.81%
Ear Disorder: 24 people, 25.81%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 24 people, 25.81%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 22 people, 23.66%
Hip Fracture: 15 people, 16.13%
Asthma: 13 people, 13.98%
High Blood Pressure: 9 people, 9.68%
Transitional Cell Carcinoma (cancer tumour inner most layer of urinary system): 8 people, 8.60%
Lung Cancer - Small Cell (lung cancer): 8 people, 8.60%

* Approximation only. Some reports may have incomplete information.

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