Adcirca and Alprostadil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adcirca (tadalafil) and Alprostadil (alprostadil). Common drug interactions include anaemia among females and interstitial lung disease among males.

The phase IV clinical study analyzes what interactions people have when they take Adcirca and Alprostadil. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Adcirca?

Adcirca has active ingredients of tadalafil. It is often used in pulmonary hypertension. eHealthMe is studying from 54,957 Adcirca users. Check the latest studies of Adcirca.

What is Alprostadil?

Alprostadil has active ingredients of alprostadil. It is often used in erection problems. eHealthMe is studying from 2,653 Alprostadil users. Check the latest studies of Alprostadil.



On Aug, 11, 2026

15 people who take Adcirca and Alprostadil together, and have interactions are studied.

Adcirca and Alprostadil drug interactions.

What are the common drug interactions of Adcirca and Alprostadil, by gender? *:

female:

  1. Anaemia (lack of blood)
  2. Bronchial fistula
  3. Dyspnoea (difficult or laboured respiration)
  4. Interstitial lung disease
  5. Lung neoplasm malignant (cancer tumour of lung)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  8. Femur fracture
  9. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  10. Post procedural complication

male:

  1. Interstitial lung disease

What are the common drug interactions of Adcirca and Alprostadil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Lymphoma (cancer that begins in immune system cells)

50-59:

  1. Bacteraemia (presence of bacteria in the blood)
  2. Septic shock (shock due to blood infection)
  3. Interstitial lung disease
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint)

60+:

  1. Anaemia (lack of blood)
  2. Femur fracture
  3. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  4. Post procedural complication
  5. Right ventricular failure (right half of the heart fails to work)
  6. Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
  7. Bronchial fistula
  8. Dyspnoea (difficult or laboured respiration)
  9. Interstitial lung disease
  10. Lung neoplasm malignant (cancer tumour of lung)

What are the existing conditions these people have? *

  1. Skin Ulcer: 5 people, 33.33%
  2. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 33.33%
  3. Insomnia (sleeplessness): 4 people, 26.67%
  4. High Blood Pressure: 4 people, 26.67%
  5. Stable Angina (a constant chest pain): 3 people, 20.00%
  6. Hepatic Function Abnormal: 3 people, 20.00%
  7. Embolism Venous (embolus may pass into the arterial system): 3 people, 20.00%
  8. Dyslipidaemia (abnormal amount of lipids): 3 people, 20.00%
  9. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.67%
  10. Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Adcirca and Alprostadil?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Adcirca and Alprostadil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Adcirca:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Alprostadil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adcirca and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alprostadil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tadalafil and alprostadil (the active ingredients of Adcirca and Alprostadil, respectively), and Adcirca and Alprostadil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: