Adcirca and Risperidone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adcirca (tadalafil) and Risperidone (risperidone). Common drug interactions include headache among females and cerebrovascular accident among males.

The phase IV clinical study analyzes what interactions people have when they take Adcirca and Risperidone. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Adcirca?

Adcirca has active ingredients of tadalafil. It is often used in pulmonary hypertension. eHealthMe is studying from 54,957 Adcirca users. Check the latest studies of Adcirca.

What is Risperidone?

Risperidone has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 72,175 Risperidone users. Check the latest studies of Risperidone.

On Jul, 08, 2026

34 people who take Adcirca and Risperidone together, and have interactions are studied.

Adcirca and Risperidone drug interactions.

What are the common drug interactions of Adcirca and Risperidone, by gender? *:

female:

Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Chest pain
Malaise (a feeling of general discomfort or uneasiness)
Palpitations (feelings or sensations that your heart is pounding or racing)
Dizziness
Cardiac failure
Hypoglycaemia (deficiency of glucose in the bloodstream)
Diarrhoea
Pulmonary oedema (fluid accumulation in the lungs)

male:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dyspnoea (difficult or laboured respiration)
Circulatory collapse
Haematuria (presence of blood in urine)
Headache (pain in head)
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Vomiting
Weight increased
Alanine aminotransferase increased
Anxiety

What are the common drug interactions of Adcirca and Risperidone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Bradycardia (abnormally slow heart action)
Cardiac failure
Circulatory collapse

10-19:

n/a

20-29:

n/a

30-39:

Nausea (feeling of having an urge to vomit)
Headache (pain in head)
Chest pain
Malaise (a feeling of general discomfort or uneasiness)
Palpitations (feelings or sensations that your heart is pounding or racing)
Dizziness
Cardiac failure
Hypoglycaemia (deficiency of glucose in the bloodstream)
Extrasystoles
Arthralgia (joint pain)

40-49:

Anxiety
Blood pressure diastolic increased
Gallbladder disorder
Headache (pain in head)
Vomiting
Weight increased

50-59:

Pulmonary oedema (fluid accumulation in the lungs)
Fluid retention (an abnormal accumulation of fluid in the blood)
Dyspnoea (difficult or laboured respiration)
Constipation
Oedema peripheral (superficial swelling)
Syncope (loss of consciousness with an inability to maintain postural tone)
Weight increased

60+:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Electrocardiogram qt prolonged
Fatigue (feeling of tiredness)
Fluid retention (an abnormal accumulation of fluid in the blood)
Haematuria (presence of blood in urine)
Hypoxia (low oxygen in tissues)
Insomnia (sleeplessness)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 28 people, 82.35%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 17.65%
Hypokalemia (low potassium): 6 people, 17.65%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 6 people, 17.65%
Gastritis - Chronic (long lasting inflammation of stomach): 6 people, 17.65%
Diabetes: 6 people, 17.65%
Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 6 people, 17.65%
Right Ventricular Failure (right half of the heart fails to work): 2 people, 5.88%
Depression: 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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