Adderall 10 and Hydroxyzine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall 10 (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Hydroxyzine (hydroxyzine hydrochloride). Common drug interactions include clostridial infection among females and generalised anxiety disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall 10 and Hydroxyzine. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall 10?

Adderall 10 has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 5,182 Adderall 10 users. Check the latest studies of Adderall 10.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.

On Jul, 08, 2026

15 people who take Adderall 10 and Hydroxyzine together, and have interactions are studied.

Adderall 10 and Hydroxyzine drug interactions.

What are the common drug interactions of Adderall 10 and Hydroxyzine, by gender? *:

female:

Clostridial infection (infectious conditions by clostridium bacteria)
Dehydration (dryness resulting from the removal of water)
Hallucination, visual (seeing things that aren't there)
Subcutaneous abscess
Hallucination (an experience involving the perception of something not present)
Nasal septum ulceration (ulcers on nasal septum)
Antisocial behaviour
Dizziness
Drug abuse
Drug ineffective

male:

Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)
Panic attack
Homicidal ideation (thoughts about human killing another human)
Mood swings (an extreme or rapid change in mood)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Suicidal ideation
Acute myocardial infarction (acute heart attack)
Conjunctivitis (pink eye)
Erythema multiforme (a type of hypersensitivity reaction)
Keratitis (eye's cornea, the front part of the eye, becomes inflamed)

What are the common drug interactions of Adderall 10 and Hydroxyzine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Aggression
Homicidal ideation (thoughts about human killing another human)
Mood swings (an extreme or rapid change in mood)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Suicidal ideation
Conjunctivitis (pink eye)
Erythema multiforme (a type of hypersensitivity reaction)
Keratitis (eye's cornea, the front part of the eye, becomes inflamed)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

30-39:

Fibromyalgia (a long-term condition which causes pain all over the body)
Headache (pain in head)
Influenza like illness

40-49:

Adverse event
Panic attack
Social problem
Speech disorder
Subcutaneous abscess
Hallucination (an experience involving the perception of something not present)
Nasal septum ulceration (ulcers on nasal septum)
Antisocial behaviour
Dizziness
Drug abuse

50-59:

Acute myocardial infarction (acute heart attack)

60+:

n/a

What are the existing conditions these people have? *

Quit Smoking: 7 people, 46.67%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 20.00%
Sleep Disorder: 2 people, 13.33%
Nicotine Dependence: 2 people, 13.33%
Irritable Bowel Syndrome: 2 people, 13.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 6.67%
Menopause (end of monthly cycles in women): 1 person, 6.67%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 6.67%
Insomnia (sleeplessness): 1 person, 6.67%
Infection: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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