Adderall 10 and Meridia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall 10 (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Meridia (sibutramine hydrochloride). Common drug interactions include pulmonary hypertension among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall 10 and Meridia. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall 10?

Adderall 10 has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 5,182 Adderall 10 users. Check the latest studies of Adderall 10.

What is Meridia?

Meridia has active ingredients of sibutramine hydrochloride. It is often used in weight loss. eHealthMe is studying from 6,939 Meridia users. Check the latest studies of Meridia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 30, 2026

19 people who take Adderall 10 and Meridia together, and have interactions are studied.

Adderall 10 and Meridia drug interactions.

What are the common drug interactions of Adderall 10 and Meridia, by gender? *:

female:

  1. Pulmonary hypertension (increase in blood pressure in the lung artery)
  2. Pyrexia (fever)
  3. Cardiomegaly (increased size of heart than normal)
  4. Chest pain
  5. Dilatation ventricular
  6. Dyspnoea exertional (breathlessness or shortness of breath)
  7. Respiratory distress (difficulty in breathing)
  8. Tricuspid valve incompetence (inefficient heart valve)
  9. Pericardial effusion (fluid around the heart)
  10. Anxiety

male:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
  3. Impaired fasting glucose
  4. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  5. Weight increased

What are the common drug interactions of Adderall 10 and Meridia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
  3. Impaired fasting glucose
  4. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  5. Weight increased

20-29:

n/a

30-39:

  1. Cough
  2. Headache (pain in head)
  3. Sinusitis (inflammation of sinus)
  4. Sore throat (pain or irritation of the throat)

40-49:

  1. Pulmonary hypertension (increase in blood pressure in the lung artery)
  2. Pyrexia (fever)
  3. Respiratory distress (difficulty in breathing)
  4. Tricuspid valve incompetence (inefficient heart valve)
  5. Pericardial effusion (fluid around the heart)
  6. Cardiac failure congestive
  7. Flushing (the warm, red condition of human skin)
  8. Dysphonia (speech disorder attributable to a disorder of phonation)
  9. Hyperhidrosis (abnormally increased sweating)
  10. Mitral valve incompetence (inefficient heart valve)

50-59:

  1. Anxiety
  2. Back pain
  3. Blood cholesterol increased
  4. Emotional disorder
  5. Fatigue (feeling of tiredness)
  6. Insomnia (sleeplessness)
  7. Tremor (trembling or shaking movements in one or more parts of your body)
  8. Arthralgia (joint pain)
  9. Blood triglycerides increased
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

60+:

n/a

What are the existing conditions these people have? *

  1. Sleep Disorder: 12 people, 63.16%
  2. Depression: 12 people, 63.16%
  3. Belching (release of gas from the digestive tract): 3 people, 15.79%
  4. Type 2 Diabetes: 1 person, 5.26%
  5. Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 1 person, 5.26%
  6. Bipolar Disorder (mood disorder): 1 person, 5.26%
  7. Back Pain: 1 person, 5.26%
  8. Aggression: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Adderall 10 and Meridia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Adderall 10:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Meridia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adderall 10 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Meridia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate and sibutramine hydrochloride (the active ingredients of Adderall 10 and Meridia, respectively), and Adderall 10 and Meridia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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