Adrenal cortex and Simulect drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adrenal cortex (adrenal extract) and Simulect (basiliximab). Common drug interactions include acute graft versus host disease among females and post transplant distal limb syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Adrenal cortex and Simulect. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Adrenal cortex?

Adrenal cortex has active ingredients of adrenal extract. eHealthMe is studying from 88 Adrenal cortex users. Check the latest studies of Adrenal cortex.

What is Simulect?

Simulect has active ingredients of basiliximab. eHealthMe is studying from 3,861 Simulect users. Check the latest studies of Simulect.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

11 people who take Adrenal cortex and Simulect together, and have interactions are studied.

Adrenal cortex and Simulect drug interactions.

What are the common drug interactions of Adrenal Cortex and Simulect, by gender? *:

female:

Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Bacteraemia (presence of bacteria in the blood)
Bone marrow failure
Diarrhoea
Exfoliative rash (scaly red generalized skin rash)
General physical health deterioration (weak health status)
Hypotension (abnormally low blood pressure)
Pain

male:

Post transplant distal limb syndrome
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Bacterial infection
Bile duct stenosis (abnormal narrowing of the common bile duct)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cholangitis (infection of the bile duct)
Cytomegalovirus infection
Drug ineffective
Hepatic failure (liver failure)
Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)

What are the common drug interactions of Adrenal Cortex and Simulect, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Bacteraemia (presence of bacteria in the blood)
Diarrhoea
General physical health deterioration (weak health status)
Rash generalised (rash on most of body parts)
Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Bone marrow failure
Exfoliative rash (scaly red generalized skin rash)

40-49:

Cytomegalovirus infection
Hepatic failure (liver failure)
Hepatitis (inflammation of the liver)
Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)

50-59:

Ureteric stenosis (abnormal narrowing or contraction of a duct or canal)

60+:

Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Immunosuppressant drug level increased
Metastases to liver (cancer spreads to liver)

What are the existing conditions these people have? *

Renal And Pancreas Transplant Rejection: 3 people, 27.27%
Immunodeficiency Disorders: 2 people, 18.18%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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