Adrenalin and Tylenol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adrenalin (epinephrine) and Tylenol (acetaminophen). Common drug interactions include acute respiratory failure among females and cytokine release syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Adrenalin and Tylenol. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Adrenalin?

Adrenalin has active ingredients of epinephrine. eHealthMe is studying from 853 Adrenalin users. Check the latest studies of Adrenalin.

What is Tylenol?

Tylenol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 222,309 Tylenol users. Check the latest studies of Tylenol.

On Jul, 30, 2026

39 people who take Adrenalin and Tylenol together, and have interactions are studied.

Adrenalin and Tylenol drug interactions.

What are the common drug interactions of Adrenalin and Tylenol, by gender? *:

female:

Acute respiratory failure
Anaemia (lack of blood)
Anaemia postoperative
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Balance disorder
Cardiogenic shock (inadequate circulation of blood)
Chronic left ventricular failure (long lasting functional impairment of left ventricle of heart)
Confusional state

male:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Pyrexia (fever)
Septic shock (shock due to blood infection)
Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
Blood lactic acid increased
Bone marrow failure
Bradycardia (abnormally slow heart action)
Cytokine storm (over-protective immune response that can actually be fatal)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematuria (presence of blood in urine)

What are the common drug interactions of Adrenalin and Tylenol, by age (0-1 to 60+)? *:

0-1:

Abdominal infection
Activated partial thromboplastin time prolonged
Alanine aminotransferase increased
Ammonia decreased
Anion gap increased
Aspartate aminotransferase increased
Blast cell count increased
Blood albumin decreased
Blood calcium decreased
Blood chloride increased

2-9:

n/a

10-19:

Pericardial effusion (fluid around the heart)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Hypoxia (low oxygen in tissues)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Pyrexia (fever)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Blood creatinine increased
Blood urea increased
Respiratory failure (inadequate gas exchange by the respiratory system)
Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)

20-29:

Chest pain

30-39:

Septic shock (shock due to blood infection)
Abdominal pain
Confusional state
Drug ineffective
Febrile neutropenia (fever with reduced white blood cells)
Influenza
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Nausea (feeling of having an urge to vomit)
Neutropenic colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)

40-49:

Agitation (state of anxiety or nervous excitement)
Confusional state
Depression
Encephalopathy (functioning of the brain is affected by some agent or condition)
Klebsiella infection
Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)
Pyrexia (fever)

50-59:

Asthenia (weakness)
Acute respiratory failure
Anaemia postoperative
Cardiogenic shock (inadequate circulation of blood)
Chronic kidney disease
Heart valve replacement
Pyrexia (fever)
Renal failure (kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Weight decreased

60+:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Nausea (feeling of having an urge to vomit)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Dehydration (dryness resulting from the removal of water)
Depression
Dizziness
Dry mouth
Dry skin
Fatigue (feeling of tiredness)
Fungaemia (fungi circulate in the blood)

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 6 people, 15.38%
Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 6 people, 15.38%
Cough: 5 people, 12.82%
Stress And Anxiety: 4 people, 10.26%
Hypersensitivity: 4 people, 10.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 10.26%
Depression: 3 people, 7.69%
High Blood Cholesterol: 3 people, 7.69%
Nausea (feeling of having an urge to vomit): 3 people, 7.69%
Multiple Myeloma (cancer of the plasma cells): 3 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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