Advair hfa and Sublimaze drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Advair hfa (fluticasone propionate; salmeterol xinafoate) and Sublimaze (fentanyl citrate). Common drug interactions include diarrhoea among females and atelectasis among males.

The phase IV clinical study analyzes what interactions people have when they take Advair hfa and Sublimaze. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Advair hfa?

Advair hfa has active ingredients of fluticasone propionate; salmeterol xinafoate. It is often used in asthma. eHealthMe is studying from 69,790 Advair hfa users. Check the latest studies of Advair hfa.

What is Sublimaze?

Sublimaze has active ingredients of fentanyl citrate. eHealthMe is studying from 560 Sublimaze users. Check the latest studies of Sublimaze.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

13 people who take Advair hfa and Sublimaze together, and have interactions are studied.

Advair hfa and Sublimaze drug interactions.

What are the common drug interactions of Advair Hfa and Sublimaze, by gender? *:

female:

Diarrhoea
Hypoxia (low oxygen in tissues)
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Pyrexia (fever)
Blood cholesterol increased
Blood glucose increased
Carotid artery occlusion (artery blockage)
Carotid artery stenosis (narrowing of carotid artery)
Dyspnoea (difficult or laboured respiration)
Hypophagia (reduced food intake)

male:

Atelectasis (partial or complete collapse of the lung)
Blood creatinine increased
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal pain
Bladder cancer
Cardiomegaly (increased size of heart than normal)
Chronic kidney disease
Drug hypersensitivity
Flatulence (flatus expelled through the anus)
Hydronephrosis (water inside the kidney)

What are the common drug interactions of Advair Hfa and Sublimaze, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain
Bladder cancer
Chronic kidney disease
Drug hypersensitivity
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

50-59:

Chronic kidney disease
Death
Renal failure (kidney dysfunction)

60+:

Diarrhoea
Hypoxia (low oxygen in tissues)
Loss of consciousness
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Oxygen consumption increased
Oxygen saturation decreased
Presyncope
Syncope (loss of consciousness with an inability to maintain postural tone)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Blood creatinine increased

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 30.77%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 23.08%
Pain: 3 people, 23.08%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 15.38%
Rashes (redness): 2 people, 15.38%
Back Pain: 2 people, 15.38%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 15.38%
Dyspnea (difficult or laboured breathing): 2 people, 15.38%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 15.38%
Urinary Tract Infection: 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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