Advil and Grape seed drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Advil (ibuprofen) and Grape seed (grape). Common drug interactions include malabsorption among females and cerebrovascular accident among males.

The phase IV clinical study analyzes what interactions people have when they take Advil and Grape seed. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,534 Advil users. Check the latest studies of Advil.

What is Grape seed?

Grape seed has active ingredients of grape. eHealthMe is studying from 893 Grape seed users. Check the latest studies of Grape seed.

On Aug, 10, 2026

23 people who take Advil and Grape seed together, and have interactions are studied.

What are the common drug interactions of Advil and Grape Seed, by gender? *:

female:

Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
Nervousness
Pancreatitis chronic (chronic inflammation of pancreas)
Peripheral swelling
Rash erythematous (redness of the skin)
Therapeutic response unexpected
Anaemia (lack of blood)
Cellulitis (infection under the skin)
Death
Dyspnoea (difficult or laboured respiration)

male:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Depression
Antiphospholipid antibodies positive
Anxiety
Aspartate aminotransferase increased
Asthenia (weakness)
Atrophic vulvovaginitis (inflammation of the vulva)
Back pain
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Blepharospasm (any abnormal contraction or twitch of the eyelid)

What are the common drug interactions of Advil and Grape Seed, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Alanine aminotransferase increased
Anaemia (lack of blood)
Aspartate aminotransferase increased
Cellulitis (infection under the skin)
Death
Dyspnoea (difficult or laboured respiration)
General physical health deterioration (weak health status)
Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
Granuloma (a small area of inflammation due to tissue injury)
Hydronephrosis (water inside the kidney)

40-49:

Injection site bruising
Injection site erythema (redness at injection site)
Muscle spasms (muscle contraction)
Muscle twitching
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)
Pain of skin
Poverty of speech

50-59:

Peripheral swelling
Rash erythematous (redness of the skin)
Therapeutic response unexpected
Tremor (trembling or shaking movements in one or more parts of your body)
Asthenia (weakness)
Depression
Influenza like illness
Loss of control of legs
Loss of libido (loss of sexual urge)
Suicidal ideation

60+:

Aspartate aminotransferase increased
Activated partial thromboplastin time prolonged
Abdominal pain
Actinic keratosis (skin disease due to sun exposure)
Adhesion
Amaurosis fugax (painless transient monocular visual loss)
Angiolipoma (a benign tumour composed chiefly of fat cells)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankylosing spondylitis (type of arthritis affecting the spine)
Antiphospholipid antibodies positive

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 4 people, 17.39%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 17.39%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 17.39%
Heart Rate Increased: 4 people, 17.39%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 17.39%
Neoplasm Malignant (cancer tumour): 3 people, 13.04%
Seasonal Allergy (allergic condition due to certain season): 2 people, 8.70%
Rickets (softening of bones): 2 people, 8.70%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 2 people, 8.70%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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