Advil and Hydroxyurea drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Advil (ibuprofen) and Hydroxyurea (hydroxyurea). Common drug interactions include nausea among females and chest pain among males.
The phase IV clinical study analyzes what interactions people have when they take Advil and Hydroxyurea. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.
What is Advil?
Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,533 Advil users. Check the latest studies of Advil.
What is Hydroxyurea?
Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.
70 people who take Advil and Hydroxyurea together, and have interactions are studied.

What are the common drug interactions of Advil and Hydroxyurea, by gender? *:
female:
- Nausea (feeling of having an urge to vomit)
- Diarrhoea
- Pain in extremity
- Fatigue (feeling of tiredness)
- Vision blurred
- Vomiting
- Contusion (a type of hematoma of tissue in which capillaries)
- Dizziness
- Ill-defined disorder
- Palpitations (feelings or sensations that your heart is pounding or racing)
male:
- Chest pain
- Fatigue (feeling of tiredness)
- Myelofibrosis (a disease in which abnormal blood cells and fibres build up inside the bone marrow)
- Oropharyngeal pain
- Toothache (tooth pain)
- Urine output decreased
- White blood cell count increased
- Pain in extremity
- White blood cell count decreased
- Abdominal pain
What are the common drug interactions of Advil and Hydroxyurea, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Oropharyngeal discomfort (pain or irritation of oropharynx)
- Platelet disorder
- Abdominal pain
20-29:
- Arthralgia (joint pain)
- Asthma
- Chest discomfort
- Chest pain
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Diarrhoea
- Fatigue (feeling of tiredness)
- Nausea (feeling of having an urge to vomit)
- Pain in extremity
- Screaming (a long loud piercing cry)
30-39:
n/a
40-49:
n/a
50-59:
- White blood cell count decreased
- Chest pain
- Ill-defined disorder
- Myalgia (muscle pain)
- Pain in extremity
- Vision blurred
- Cough
- Full blood count decreased
- Hunger
- Hypophagia (reduced food intake)
60+:
- Contusion (a type of hematoma of tissue in which capillaries)
- Death
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Platelet count decreased
- Splenomegaly (enlargement of spleen)
- White blood cell count decreased
- Diarrhoea
- Dysgeusia (disorder of the sense of taste)
- Epistaxis (bleed from the nose)
- Flushing (the warm, red condition of human skin)
What are the existing conditions these people have? *
- Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 27 people, 38.57%
- Primary Myelofibrosis (primary disorder of the bone marrow): 19 people, 27.14%
* Approximation only. Some reports may have incomplete information.
Do you take Advil and Hydroxyurea?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Advil (62,533 reports)
- Hydroxyurea (17,240 reports)
Browse all drug interactions of Advil and Hydroxyurea:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Advil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Hydroxyurea:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Advil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hydroxyurea and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on ibuprofen and hydroxyurea (the active ingredients of Advil and Hydroxyurea, respectively), and Advil and Hydroxyurea (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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