Advil and Lotrisone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Advil (ibuprofen) and Lotrisone (betamethasone dipropionate; clotrimazole). Common drug interactions include pyrexia among females and salivary gland calculus among males.
The phase IV clinical study analyzes what interactions people have when they take Advil and Lotrisone. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.
What is Advil?
Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,533 Advil users. Check the latest studies of Advil.
What is Lotrisone?
Lotrisone has active ingredients of betamethasone dipropionate; clotrimazole. eHealthMe is studying from 1,819 Lotrisone users. Check the latest studies of Lotrisone.
32 people who take Advil and Lotrisone together, and have interactions are studied.

What are the common drug interactions of Advil and Lotrisone, by gender? *:
female:
- Pyrexia (fever)
- Rales (an abnormal respiratory sound characterized by fine crackles)
- Renal failure (kidney dysfunction)
- Renal failure chronic (long lasting kidney dysfunction)
- Renal hypertension (high blood pressure caused by the kidneys hormonal response)
- Respiratory rate increased (excess breathing rate/min)
- Restless legs syndrome (a powerful urge to move your legs)
- Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
- Rhinorrhoea (watery mucus discharge from the nose)
- Road traffic accident
male:
- Salivary gland calculus (stone in salivary gland)
- Anxiety
- Depression
- Drug hypersensitivity
- Drug resistance (reduction in effectiveness of a drug)
- Dyskinesia (abnormality or impairment of voluntary movement)
- Gait disturbance
- Hyperacusis (disorder in loudness perception)
- Hypertension (high blood pressure)
- Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
What are the common drug interactions of Advil and Lotrisone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Drug hypersensitivity
- Hyperacusis (disorder in loudness perception)
- Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Streptococcal infection
- Road traffic accident
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Affective disorder (mental disorder)
40-49:
- Salivary gland calculus (stone in salivary gland)
- Anxiety
- Back pain
- Emotional distress
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Arrhythmia (irregular heartbeat)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Blood creatinine increased
50-59:
- Bronchial irritation
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
- Cough
- Pharyngeal inflammation
60+:
- Abdominal pain
- Colon adenoma (non cancerous epithelial colon tumour having a glandular origin and structure)
- Anaemia (lack of blood)
- Arthralgia (joint pain)
- Chest pain
- Constipation
- Cystitis interstitial (unknown cause characterized by bladder pain)
- Decreased appetite
- Diarrhoea
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
What are the existing conditions these people have? *
- Insomnia (sleeplessness): 7 people, 21.88%
- Headache (pain in head): 7 people, 21.88%
- Cheilitis (infection of lips): 6 people, 18.75%
- Itching: 6 people, 18.75%
- Hepatitis C: 6 people, 18.75%
- Wheezing (a high-pitched whistling sound made while you breath): 5 people, 15.62%
- High Blood Pressure: 5 people, 15.62%
- Dyspnea (difficult or laboured breathing): 4 people, 12.50%
- Osteoporosis (bones weak and more likely to break): 3 people, 9.38%
- Cough: 3 people, 9.38%
* Approximation only. Some reports may have incomplete information.
Do you take Advil and Lotrisone?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Advil and Lotrisone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Advil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lotrisone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Advil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lotrisone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on ibuprofen and betamethasone dipropionate; clotrimazole (the active ingredients of Advil and Lotrisone, respectively), and Advil and Lotrisone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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