Advil and Migranal drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Advil (ibuprofen) and Migranal (dihydroergotamine mesylate). Common drug interactions include dyspnoea among females.
The phase IV clinical study analyzes what interactions people have when they take Advil and Migranal. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Advil?
Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,533 Advil users. Check the latest studies of Advil.
What is Migranal?
Migranal has active ingredients of dihydroergotamine mesylate. It is often used in migraine. eHealthMe is studying from 560 Migranal users. Check the latest studies of Migranal.
20 people who take Advil and Migranal together, and have interactions are studied.

What are the common drug interactions of Advil and Migranal, by gender? *:
female:
- Dyspnoea (difficult or laboured respiration)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Disturbance in attention
- Epistaxis (bleed from the nose)
- Feeling of despair
- Gingival bleeding (bleeding gums)
- Injection site haematoma (localized swelling filled with blood at injection site)
- Injection site haemorrhage (bleeding from injection site)
- Joint ankylosis (a stiffness of a joint due to abnormal adhesion and rigidity of the bones of the joint)
male:
n/a
What are the common drug interactions of Advil and Migranal, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Pulmonary embolism (blockage of the main artery of the lung)
- Chest pain
- Dyspnoea (difficult or laboured respiration)
- Epistaxis (bleed from the nose)
- Gallbladder injury
- Gingival bleeding (bleeding gums)
- Injection site haematoma (localized swelling filled with blood at injection site)
- Injection site haemorrhage (bleeding from injection site)
- Joint ankylosis (a stiffness of a joint due to abnormal adhesion and rigidity of the bones of the joint)
30-39:
- Adjustment disorder
- Drug abuse
- Dysthymic disorder (mild chronic depression disorder)
- Dysuria (painful or difficult urination)
- Eye pain
- Gallbladder injury
- Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
- Haematuria (presence of blood in urine)
- Haemorrhagic ovarian cyst (bleeding ovarian cyst)
- Homicidal ideation (thoughts about human killing another human)
40-49:
n/a
50-59:
n/a
60+:
- Drug ineffective
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 30.00%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 25.00%
- Heavy Or Prolong Menstrual Bleeding: 3 people, 15.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 15.00%
- Acne (skin problems that cause pimples): 3 people, 15.00%
- Depression: 2 people, 10.00%
- Thrombocytopenia (decrease of platelets in blood): 1 person, 5.00%
- Stress And Anxiety: 1 person, 5.00%
- Insomnia (sleeplessness): 1 person, 5.00%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Advil and Migranal?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Advil and Migranal:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Advil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Migranal:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Advil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Migranal and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on ibuprofen and dihydroergotamine mesylate (the active ingredients of Advil and Migranal, respectively), and Advil and Migranal (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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