Advil and Pentoxifylline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Advil (ibuprofen) and Pentoxifylline (pentoxifylline). Common drug interactions include chronic kidney disease among females and posterior reversible encephalopathy syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Advil and Pentoxifylline. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,534 Advil users. Check the latest studies of Advil.

What is Pentoxifylline?

Pentoxifylline has active ingredients of pentoxifylline. eHealthMe is studying from 5,997 Pentoxifylline users. Check the latest studies of Pentoxifylline.

On Aug, 07, 2026

18 people who take Advil and Pentoxifylline together, and have interactions are studied.

Advil and Pentoxifylline drug interactions.

What are the common drug interactions of Advil and Pentoxifylline, by gender? *:

female:

Chronic kidney disease
Asthenia (weakness)
Dehydration (dryness resulting from the removal of water)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Full blood count decreased
Nephrogenic anaemia (anaemia due to kidney disease)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pulmonary oedema (fluid accumulation in the lungs)
Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)

male:

Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Abscess limb (limb infection)
Constipation
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Labyrinthitis (inflammation of the labyrinth or inner ear)
Malaise (a feeling of general discomfort or uneasiness)
Spinal compression fracture (fracture due to spinal compression on bone)
Abscess (pus)
Balance disorder
Blood glucose increased

What are the common drug interactions of Advil and Pentoxifylline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Generalised oedema (swelling all over the body)
Asthenia (weakness)
Chronic kidney disease
Dehydration (dryness resulting from the removal of water)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Full blood count decreased
Nephrogenic anaemia (anaemia due to kidney disease)
Palpitations (feelings or sensations that your heart is pounding or racing)
Renal failure (kidney dysfunction)

60+:

Abscess limb (limb infection)
Cellulitis (infection under the skin)
Diplopia (double vision)
Dizziness
Fall
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Heart rate decreased
Inflammation
Insomnia (sleeplessness)
Labyrinthitis (inflammation of the labyrinth or inner ear)

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 44.44%
High Blood Cholesterol: 6 people, 33.33%
Oedema (fluid collection in tissue): 6 people, 33.33%
Muscle Aches (muscle pain): 5 people, 27.78%
Insomnia (sleeplessness): 5 people, 27.78%
Multiple Allergies (allergy to multiple agents): 4 people, 22.22%
Glaucoma (increased fluid pressure in the eye with vision loss): 4 people, 22.22%
Heart Disease: 4 people, 22.22%
Stress And Anxiety: 4 people, 22.22%
Cholangiocarcinoma (a cancer that forms glands or secretes significant amounts of mucins): 4 people, 22.22%

* Approximation only. Some reports may have incomplete information.

Do you take Advil and Pentoxifylline?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously