Advil and Rezulin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Advil (ibuprofen) and Rezulin (troglitazone). Common drug interactions include arthralgia among females and renal impairment among males.
The phase IV clinical study analyzes what interactions people have when they take Advil and Rezulin. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Advil?
Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,533 Advil users. Check the latest studies of Advil.
What is Rezulin?
Rezulin has active ingredients of troglitazone. eHealthMe is studying from 8,764 Rezulin users. Check the latest studies of Rezulin.
12 people who take Advil and Rezulin together, and have interactions are studied.

What are the common drug interactions of Advil and Rezulin, by gender? *:
female:
- Arthralgia (joint pain)
- Chest pain
- Depression
- Dyspnoea (difficult or laboured respiration)
- Oedema lower limb (fluid collection in tissue of lower leg)
- Abdominal adhesions (inflammation of abdomen)
- Abdominal pain
- Acute pre-renal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
- Alopecia (absence of hair from areas of the body)
- Anaemia (lack of blood)
male:
- Renal impairment (severely reduced kidney function)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Stress
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
- Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
- Hepatic failure (liver failure)
- Hepatic neoplasm malignant (liver cancer)
- Insomnia (sleeplessness)
- Liver fatty (fat deposition of liver)
What are the common drug interactions of Advil and Rezulin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Chest pain
- Depression
- Dyspnoea (difficult or laboured respiration)
- Oedema lower limb (fluid collection in tissue of lower leg)
- Acute pre-renal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
- Anaemia (lack of blood)
- Arthralgia (joint pain)
- Asthma
- Bartholin's cyst (cyst is formed on one or both of the two bartholin's glands, which are located one on either side of the opening of the vagina)
- Bladder pain
50-59:
- Liver fatty (fat deposition of liver)
- Abdominal adhesions (inflammation of abdomen)
- Abdominal pain
- Anxiety
- Arthralgia (joint pain)
- Blood bilirubin increased
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Drug ineffective
- Glycosylated haemoglobin increased
60+:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Stress
- Myalgia (muscle pain)
- Alopecia (absence of hair from areas of the body)
- Diarrhoea
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Insomnia (sleeplessness)
- Loose stools
- Muscle weakness (a lack of muscle strength)
What are the existing conditions these people have? *
- Type 2 Diabetes: 1 person, 8.33%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Advil and Rezulin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Advil and Rezulin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Advil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Rezulin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Advil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rezulin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on ibuprofen and troglitazone (the active ingredients of Advil and Rezulin, respectively), and Advil and Rezulin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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