Advil and Trileptal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Advil (ibuprofen) and Trileptal (oxcarbazepine). Common drug interactions include back pain among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Advil and Trileptal. It is created by eHealthMe based on reports of 91 people who take the same drugs from the FDA, and is updated regularly.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,533 Advil users. Check the latest studies of Advil.

What is Trileptal?

Trileptal has active ingredients of oxcarbazepine. It is often used in bipolar disorder. eHealthMe is studying from 23,558 Trileptal users. Check the latest studies of Trileptal.

On Jul, 26, 2026

91 people who take Advil and Trileptal together, and have interactions are studied.

What are the common drug interactions of Advil and Trileptal, by gender? *:

female:

Back pain
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Chest pain
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Cough
Hyperhidrosis (abnormally increased sweating)
Myalgia (muscle pain)

male:

Weight decreased
Gait disturbance
Decreased appetite
Trigeminal neuralgia (a painful condition of the nerve responsible for most facial sensation)
Neuropathy peripheral (surface nerve damage)
Abdominal pain upper
Balance disorder
Constipation
Hypoaesthesia (reduced sense of touch or sensation)
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Advil and Trileptal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Acute respiratory failure
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Tonic convulsion (the person will quickly lose consciousness and the skeletal muscles will suddenly tense, often causing the extremities to be pulled towards the body or rigidly pushed away from it)
Anaphylactic reaction (serious allergic reaction)
Hydrocephalus (water on the brain)
Pruritus (severe itching of the skin)
Rash

10-19:

Acute respiratory failure
Febrile convulsion (a convulsion associated with a significant rise in body temperature)
Lower respiratory tract infection viral
Secondary immunodeficiency (lack of immunity due to some disease)
Abdominal pain upper
Acne (skin problems that cause pimples)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Menometrorrhagia (a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal)
Mood swings (an extreme or rapid change in mood)
Weight increased

20-29:

Blepharospasm (any abnormal contraction or twitch of the eyelid)
Breech presentation
Polymorphic eruption of pregnancy (chronic hives-like rash that strikes some women during pregnancy)
Pregnancy
Stress
Chest pain
Diarrhoea
Pain in jaw
Abdominal pain
Acne (skin problems that cause pimples)

30-39:

Asthenia (weakness)
Eye pain
Fatigue (feeling of tiredness)
Somnolence (a state of near-sleep, a strong desire for sleep)
Toothache (tooth pain)
Tremor (trembling or shaking movements in one or more parts of your body)
Vision blurred
Cellulitis (infection under the skin)
Tooth infection
Hypokalaemia (low potassium)

40-49:

Visual impairment
Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Cerebral atrophy (decrement in size of brain)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Intervertebral disc degeneration (spinal disc degeneration)
Intervertebral disc protrusion (spinal disc protrusion)
Memory impairment
Neuropathy peripheral (surface nerve damage)
Pneumonia

50-59:

Cough
Feeling cold
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Hyperhidrosis (abnormally increased sweating)
Loss of consciousness
Myalgia (muscle pain)
Pyrexia (fever)
Sleep disorder
Spinal pain (pain in spine)
Vision blurred

60+:

Anaemia (lack of blood)
Arteriosclerosis (thickening and hardening of arteries)
Chest pain
Confusional state
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Decreased appetite
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 30 people, 32.97%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 9.89%
Type 2 Diabetes: 8 people, 8.79%
Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 8 people, 8.79%
Muscle Spasms (muscle contraction): 8 people, 8.79%
Migraine (headache): 7 people, 7.69%
Sleep Apnea Syndrome: 6 people, 6.59%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 6 people, 6.59%
Diabetes: 6 people, 6.59%
Depression: 6 people, 6.59%

* Approximation only. Some reports may have incomplete information.

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