Ajovy and Divalproex sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ajovy (fremanezumab-vfrm) and Divalproex sodium (divalproex sodium). Common drug interactions include drug ineffective among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Ajovy and Divalproex sodium. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Ajovy?

Ajovy has active ingredients of fremanezumab-vfrm. eHealthMe is studying from 8,834 Ajovy users. Check the latest studies of Ajovy.

What is Divalproex sodium?

Divalproex sodium has active ingredients of divalproex sodium. It is often used in epilepsy. eHealthMe is studying from 9,483 Divalproex sodium users. Check the latest studies of Divalproex sodium.



On Jul, 09, 2026

11 people who take Ajovy and Divalproex sodium together, and have interactions are studied.

Ajovy and Divalproex sodium drug interactions.

What are the common drug interactions of Ajovy and Divalproex Sodium, by gender? *:

female:

  1. Drug ineffective
  2. Abdominal discomfort
  3. Arthralgia (joint pain)
  4. Back disorder
  5. Blood pressure decreased
  6. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Headache (pain in head)
  9. Heart rate decreased
  10. Heart rate increased

male:

  1. Headache (pain in head)
  2. Agitation (state of anxiety or nervous excitement)
  3. Head injury
  4. Infection
  5. Intentional self-injury
  6. Nausea (feeling of having an urge to vomit)
  7. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  8. Pulmonary function test decreased
  9. Weight decreased
  10. Arthralgia (joint pain)

What are the common drug interactions of Ajovy and Divalproex Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Back disorder
  2. Blood pressure decreased
  3. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Heart rate decreased
  6. Heart rate increased
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Nausea (feeling of having an urge to vomit)
  9. Peripheral swelling
  10. Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)

40-49:

n/a

50-59:

  1. Drug ineffective
  2. Rash papular (redness with papule)
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Drug dependence
  5. Head injury
  6. Weight decreased

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 45.45%
  2. Migraine (headache): 5 people, 45.45%
  3. Drowsiness: 5 people, 45.45%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 45.45%
  5. High Blood Pressure: 4 people, 36.36%
  6. Migraine Without Aura (headache without neurological problems): 1 person, 9.09%
  7. Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Ajovy and Divalproex sodium?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ajovy and Divalproex sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ajovy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Divalproex sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ajovy and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Divalproex sodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fremanezumab-vfrm and divalproex sodium (the active ingredients of Ajovy and Divalproex sodium, respectively), and Ajovy and Divalproex sodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: