Ajovy and Effexor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ajovy (fremanezumab-vfrm) and Effexor (venlafaxine hydrochloride). Common drug interactions include paraesthesia among females and angina pectoris among males.

The phase IV clinical study analyzes what interactions people have when they take Ajovy and Effexor. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Ajovy?

Ajovy has active ingredients of fremanezumab-vfrm. eHealthMe is studying from 8,834 Ajovy users. Check the latest studies of Ajovy.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.

On Jul, 09, 2026

39 people who take Ajovy and Effexor together, and have interactions are studied.

What are the common drug interactions of Ajovy and Effexor, by gender? *:

female:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Somnolence (a state of near-sleep, a strong desire for sleep)
Vertigo
Drug ineffective
Fall
Injection site reaction
Rash macular (small, flat red spots)
Abdominal discomfort
Depressed level of consciousness
Eye pain

male:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Hypomania (a mild form of mania, marked by elation and hyperactivity)

What are the common drug interactions of Ajovy and Effexor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Rash macular (small, flat red spots)
Fatigue (feeling of tiredness)
Hypersomnia (excessive daytime sleepiness (eds))
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Rash pruritic (redness with itching)
Somnolence (a state of near-sleep, a strong desire for sleep)
Weight increased

30-39:

Migraine (headache)
Injection site erythema (redness at injection site)
Injection site pruritus (severe itching at injection site)
Injection site swelling
Injection site urticaria (rash of round, red welts on the skin at injection site)
Panic attack
Constipation
Dizziness
Palpitations (feelings or sensations that your heart is pounding or racing)
Self-injurious ideation

40-49:

Injection site erythema (redness at injection site)
Injection site mass
Injection site pruritus (severe itching at injection site)
Injection site reaction
Injection site warmth
Abdominal pain
Adverse drug reaction
Agitation (state of anxiety or nervous excitement)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Bladder disorder

50-59:

Fibula fracture
Tibia fracture (fracture of lower leg bone)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Contusion (a type of hematoma of tissue in which capillaries)
Haemorrhage (bleeding)
Hypersensitivity
Influenza like illness
Injection site reaction
Malaise (a feeling of general discomfort or uneasiness)

60+:

Abdominal pain lower
Bladder irritation
Fatigue (feeling of tiredness)
Fibromyalgia (a long-term condition which causes pain all over the body)
Headache (pain in head)
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Neuralgia (pain in one or more nerves)
Alopecia (absence of hair from areas of the body)

What are the existing conditions these people have? *

Migraine (headache): 20 people, 51.28%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 15.38%
Drowsiness: 4 people, 10.26%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 10.26%

* Approximation only. Some reports may have incomplete information.

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