Ajovy and Simponi drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ajovy (fremanezumab-vfrm) and Simponi (golimumab). Common drug interactions include drug hypersensitivity among females.
The phase IV clinical study analyzes what interactions people have when they take Ajovy and Simponi. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Ajovy?
Ajovy has active ingredients of fremanezumab-vfrm. eHealthMe is studying from 8,834 Ajovy users. Check the latest studies of Ajovy.
What is Simponi?
Simponi has active ingredients of golimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 86,328 Simponi users. Check the latest studies of Simponi.
11 people who take Ajovy and Simponi together, and have interactions are studied.
What are the common drug interactions of Ajovy and Simponi, by gender? *:
female:
- Drug hypersensitivity
- Malaise (a feeling of general discomfort or uneasiness)
- Dizziness
- Dysmenorrhoea (painful menstruation)
- Dysstasia (difficulty in standing)
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Infusion related reaction
- Infusion site pain
- Injection site cyst
male:
n/a
What are the common drug interactions of Ajovy and Simponi, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Injection site cyst
- Injection site extravasation (flow of (blood or lymph) from injection site)
30-39:
n/a
40-49:
- Malignant melanoma (skin cancer rises from melancytes)
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Migraine (headache): 4 people, 36.36%
- Immunodeficiency Common Variable: 4 people, 36.36%
- Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 3 people, 27.27%
- Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 27.27%
- Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 2 people, 18.18%
- Migraine Without Aura (headache without neurological problems): 2 people, 18.18%
- High Blood Cholesterol: 2 people, 18.18%
- Headache (pain in head): 2 people, 18.18%
* Approximation only. Some reports may have incomplete information.
Do you take Ajovy and Simponi?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ajovy and Simponi:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ajovy:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Simponi:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ajovy and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Simponi and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Azuma N, Matsui K, Hashimoto N, Yoshikawa T, Sano H, "Successful Switch to Golimumab for Eosinophilia and Skin Symptoms Related to Multiple Biologics in a Patient with Rheumatoid Arthritis", Internal Medicine, 2017 Jun .
- Azuma N, Matsui K, Hashimoto N, Yoshikawa T, Sano H, "Successful Switch to Golimumab for Eosinophilia and Skin Symptoms Related to Multiple Biologics in a Patient with Rheumatoid Arthritis", Internal Medicine, 2017 Jun .
How the study uses the data?
The study uses data from the FDA. It is based on fremanezumab-vfrm and golimumab (the active ingredients of Ajovy and Simponi, respectively), and Ajovy and Simponi (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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