Alavert and Hydrochlorothiazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alavert (loratadine) and Hydrochlorothiazide (hydrochlorothiazide). Common drug interactions include muscular weakness among females and arthritis among males.

The phase IV clinical study analyzes what interactions people have when they take Alavert and Hydrochlorothiazide. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Alavert?

Alavert has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 2,062 Alavert users. Check the latest studies of Alavert.

What is Hydrochlorothiazide?

Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 182,194 Hydrochlorothiazide users. Check the latest studies of Hydrochlorothiazide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

59 people who take Alavert and Hydrochlorothiazide together, and have interactions are studied.

Alavert and Hydrochlorothiazide drug interactions.

What are the common drug interactions of Alavert and Hydrochlorothiazide, by gender? *:

female:

Muscular weakness (muscle weakness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pain in extremity
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Pyuria (a condition of urine containing pus)
Rash
Red blood cell sedimentation rate increased
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Syncope (loss of consciousness with an inability to maintain postural tone)

male:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back injury
Fatigue (feeling of tiredness)
Full blood count decreased
Headache (pain in head)
Iridocele
Iris disorder
Iris injury
Localised infection (infection at the single location)
Mass

What are the common drug interactions of Alavert and Hydrochlorothiazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Abdominal mass (localized enlargement or swelling in the human abdomen)
Adrenal adenoma (benign tumour of the glandular type (adenoma) in the adrenal gland)
Agoraphobia (extreme or irrational fear of crowded spaces or enclosed public places)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Asthma
Atelectasis (partial or complete collapse of the lung)
Blood glucose increased
Body tinea (ringworm of the body)
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)

40-49:

Skin discolouration (change of skin colour)
Allergy to vaccine
Application site warmth
Atrioventricular block (heart block)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Blood urine present
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Fatigue (feeling of tiredness)
Infusion site erythema (reddening of the skin at infusion site)
Injection site scar

50-59:

Abnormal behaviour
Nausea (feeling of having an urge to vomit)
Suicide attempt
Blood copper increased
Dizziness
Fall
Fatigue (feeling of tiredness)
Headache (pain in head)
Intervertebral disc protrusion (spinal disc protrusion)
Malaise (a feeling of general discomfort or uneasiness)

60+:

Malaise (a feeling of general discomfort or uneasiness)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Headache (pain in head)
Joint injury
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)
Osteonecrosis of jaw (death of bone of jaw)
Pruritus (severe itching of the skin)
Abnormal sensation in eye
Arthritis (form of joint disorder that involves inflammation of one or more joints)

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 14 people, 23.73%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 23.73%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 11.86%
Hypersensitivity: 7 people, 11.86%
Pain: 5 people, 8.47%
Cushing's Syndrome (obesity, a rounded face, increased fat): 5 people, 8.47%
Depression: 4 people, 6.78%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 5.08%
Asthma: 3 people, 5.08%
Blood Pressure Abnormal: 3 people, 5.08%

* Approximation only. Some reports may have incomplete information.

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