Alavert and Pepcid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alavert (loratadine) and Pepcid (famotidine). Common drug interactions include anion gap increased among females and bone pain among males.

The phase IV clinical study analyzes what interactions people have when they take Alavert and Pepcid. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Alavert?

Alavert has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 2,062 Alavert users. Check the latest studies of Alavert.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,774 Pepcid users. Check the latest studies of Pepcid.



On Jul, 12, 2026

29 people who take Alavert and Pepcid together, and have interactions are studied.

Alavert and Pepcid drug interactions.

What are the common drug interactions of Alavert and Pepcid, by gender? *:

female:

  1. Anion gap increased
  2. Basophil count decreased
  3. Blood alkaline phosphatase increased
  4. Blood calcium increased
  5. Blood creatinine increased
  6. Blood glucose increased
  7. Blood immunoglobulin g increased
  8. Carbon dioxide decreased
  9. Dehydration (dryness resulting from the removal of water)
  10. Eosinophil count decreased

male:

  1. Bone pain
  2. Dyspnoea (difficult or laboured respiration)
  3. Muscle spasms (muscle contraction)
  4. Pleural effusion (water on the lungs)
  5. Skin infection
  6. Pain in extremity
  7. Renal impairment (severely reduced kidney function)
  8. Bacterial infection
  9. Chronic kidney disease
  10. Death

What are the common drug interactions of Alavert and Pepcid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Impaired gastric emptying
  3. Rash

30-39:

  1. Anion gap increased
  2. Basophil count decreased
  3. Blood alkaline phosphatase increased
  4. Blood calcium increased
  5. Blood creatinine increased
  6. Blood glucose increased
  7. Blood immunoglobulin g increased
  8. Carbon dioxide decreased
  9. Dehydration (dryness resulting from the removal of water)
  10. Eosinophil count decreased

40-49:

  1. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  2. Chronic kidney disease
  3. Depression
  4. Drug effect decreased
  5. Headache (pain in head)
  6. Intestinal obstruction
  7. Joint injury
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Muscle spasms (muscle contraction)
  10. Nausea (feeling of having an urge to vomit)

50-59:

  1. Cervical spinal stenosis (narrowing of the spinal canal in the neck)
  2. Nausea (feeling of having an urge to vomit)
  3. Road traffic accident
  4. Sluggishness (lacking alertness)
  5. Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

  1. Chronic kidney disease
  2. Drug effect decreased
  3. Disease progression
  4. Intestinal obstruction
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Nerve injury
  7. Pain
  8. Pleural effusion (water on the lungs)
  9. Pruritus (severe itching of the skin)
  10. Rash

What are the existing conditions these people have? *

  1. Pain: 9 people, 31.03%
  2. Stress And Anxiety: 6 people, 20.69%
  3. Rickets (softening of bones): 6 people, 20.69%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 20.69%
  5. Fatigue (feeling of tiredness): 5 people, 17.24%
  6. Seasonal Allergy (allergic condition due to certain season): 5 people, 17.24%
  7. Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 5 people, 17.24%
  8. Birth Control: 5 people, 17.24%
  9. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 5 people, 17.24%
  10. Suicidal Ideation: 5 people, 17.24%

* Approximation only. Some reports may have incomplete information.

Do you take Alavert and Pepcid?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Alavert and Pepcid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Alavert:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pepcid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alavert and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pepcid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on loratadine and famotidine (the active ingredients of Alavert and Pepcid, respectively), and Alavert and Pepcid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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