Alendronate sodium and Dipyrone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alendronate sodium (alendronate sodium) and Dipyrone (metamizole). Common drug interactions include pneumonia among females and hypertension among males.

The phase IV clinical study analyzes what interactions people have when they take Alendronate sodium and Dipyrone. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Alendronate sodium?

Alendronate sodium has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 43,608 Alendronate sodium users. Check the latest studies of Alendronate sodium.

What is Dipyrone?

Dipyrone has active ingredients of metamizole. eHealthMe is studying from 1,876 Dipyrone users. Check the latest studies of Dipyrone.



On Jul, 08, 2026

11 people who take Alendronate sodium and Dipyrone together, and have interactions are studied.

Alendronate sodium and Dipyrone drug interactions.

What are the common drug interactions of Alendronate Sodium and Dipyrone, by gender? *:

female:

  1. Pneumonia
  2. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  3. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  4. Fall
  5. General physical health deterioration (weak health status)
  6. Lung adenocarcinoma stage ii (the cancer has spread to some lymph nodes near the original tumour)
  7. Lung consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces)
  8. Pneumonia escherichia (pneumonia due to bacteria escherichia coli)
  9. Pruritus (severe itching of the skin)
  10. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

male:

  1. Hypertension (high blood pressure)
  2. Acute respiratory distress syndrome
  3. Cardiac valve disease (heart valve disease)
  4. Cataract (clouding of the lens inside the eye)
  5. Chest discomfort
  6. Colonoscopy
  7. Conjunctivitis (pink eye)
  8. Dyspnoea (difficult or laboured respiration)
  9. Dysstasia (difficulty in standing)
  10. Fall

What are the common drug interactions of Alendronate Sodium and Dipyrone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Anaemia postoperative
  2. Arthralgia (joint pain)
  3. Atypical femur fracture
  4. Back pain
  5. Blood alkaline phosphatase decreased
  6. Blood cholesterol increased
  7. Bone disorder
  8. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  9. Cardiac valve disease (heart valve disease)
  10. Cataract (clouding of the lens inside the eye)

60+:

  1. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Pruritus (severe itching of the skin)
  4. Acute respiratory distress syndrome
  5. Chest discomfort
  6. Conjunctivitis (pink eye)
  7. Drug effect decreased
  8. Dyspnoea (difficult or laboured respiration)
  9. Fluid retention (an abnormal accumulation of fluid in the blood)
  10. Gangrene (body tissue dies)

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 81.82%
  2. Pain: 3 people, 27.27%
  3. Gastric Disorder (disease of stomach): 2 people, 18.18%
  4. Polyarthritis (arthritis which involves 5 or more joints simultaneously): 1 person, 9.09%
  5. Hypocalcaemia (levels of calcium in blood serum are abnormally low): 1 person, 9.09%
  6. Headache (pain in head): 1 person, 9.09%
  7. Diabetes: 1 person, 9.09%
  8. Depression: 1 person, 9.09%
  9. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 9.09%
  10. Calcium Metabolism Disorder (occur when the body has too little or too much calcium): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Alendronate sodium and Dipyrone:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Alendronate sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dipyrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alendronate sodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dipyrone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on alendronate sodium and metamizole (the active ingredients of Alendronate sodium and Dipyrone, respectively), and Alendronate sodium and Dipyrone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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