Alendronate sodium and Macitentan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alendronate sodium (alendronate sodium) and Macitentan (macitentan). Common drug interactions include epistaxis among females and cardiac failure among males.

The phase IV clinical study analyzes what interactions people have when they take Alendronate sodium and Macitentan. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Alendronate sodium?

Alendronate sodium has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 43,608 Alendronate sodium users. Check the latest studies of Alendronate sodium.

What is Macitentan?

Macitentan has active ingredients of macitentan. eHealthMe is studying from 7,371 Macitentan users. Check the latest studies of Macitentan.

On Jul, 06, 2026

18 people who take Alendronate sodium and Macitentan together, and have interactions are studied.

Alendronate sodium and Macitentan drug interactions.

What are the common drug interactions of Alendronate Sodium and Macitentan, by gender? *:

female:

Epistaxis (bleed from the nose)
Haemorrhage (bleeding)
Headache (pain in head)
Hot flush (sudden feelings of heat)
Malaise (a feeling of general discomfort or uneasiness)
Oedema peripheral (superficial swelling)
Oxygen saturation decreased
Platelet count decreased
Pneumonia
Pyrexia (fever)

male:

Cardiac failure
Respiratory failure (inadequate gas exchange by the respiratory system)

What are the common drug interactions of Alendronate Sodium and Macitentan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Diarrhoea
Vomiting
Haemorrhage (bleeding)
Headache (pain in head)
Hot flush (sudden feelings of heat)
Malaise (a feeling of general discomfort or uneasiness)
Oedema peripheral (superficial swelling)
Oxygen saturation decreased
Platelet count decreased
Pneumonia

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 14 people, 77.78%
Iron Deficiency Anaemia: 8 people, 44.44%
Connective Tissue Disorder (any disease that has the connective tissues of the body): 6 people, 33.33%
Depression: 6 people, 33.33%
Hypokalemia (low potassium): 6 people, 33.33%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 6 people, 33.33%
Right Ventricular Failure (right half of the heart fails to work): 6 people, 33.33%
Salivary Gland Calculus (stone in salivary gland): 5 people, 27.78%
Sedation: 4 people, 22.22%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 22.22%

* Approximation only. Some reports may have incomplete information.

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