Alendronic acid and Fentanyl drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Alendronic acid (alendronate sodium) and Fentanyl (fentanyl citrate). Common drug interactions include skin reaction among females and pneumonia among males.
The phase IV clinical study analyzes what interactions people have when they take Alendronic acid and Fentanyl. It is created by eHealthMe based on reports of 96 people who take the same drugs from the FDA, and is updated regularly.
What is Alendronic acid?
Alendronic acid has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 18,408 Alendronic acid users. Check the latest studies of Alendronic acid.
What is Fentanyl?
Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 73,301 Fentanyl users. Check the latest studies of Fentanyl.
96 people who take Alendronic acid and Fentanyl together, and have interactions are studied.

What are the common drug interactions of Alendronic Acid and Fentanyl, by gender? *:
female:
- Skin reaction
- Ventricular fibrillation (abnormally irregular heart rhythm)
- Infection
- Oedema (fluid collection in tissue)
- Swelling face
- Abdominal pain
- Altered state of consciousness (altered state of mind)
- Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
- Arthralgia (joint pain)
- Asthenia (weakness)
male:
- Pneumonia
- Confusional state
- Mood swings (an extreme or rapid change in mood)
- Neuropathy peripheral (surface nerve damage)
- Pseudomonal sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Breast mass
- Cough
- Delirium (wild excitement)
- Dry eye (lack of adequate tears)
What are the common drug interactions of Alendronic Acid and Fentanyl, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Arthralgia (joint pain)
- Blood urine present
- Dysuria (painful or difficult urination)
- Hot flush (sudden feelings of heat)
- Hypotension (abnormally low blood pressure)
- Joint stiffness
- Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Productive cough
- Protein urine present
30-39:
n/a
40-49:
- Fistula (an abnormal connection or passageway between two)
- Gangrene (body tissue dies)
50-59:
- Constipation
- Gingivitis (inflammation of gums)
- Lower respiratory tract infection
- Oral herpes (viral infection of mouth)
- Tooth abscess (pus formation in tooth)
- Upper respiratory tract infection
- Cardiac failure
- Cardiomegaly (increased size of heart than normal)
- Drug intolerance (drug sensitivity)
- Oedema peripheral (superficial swelling)
60+:
- Malaise (a feeling of general discomfort or uneasiness)
- Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
- Cough
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
- Electrocardiogram qt prolonged
- Multi-organ failure (multisystem organ failure)
- Vomiting
- Infection
What are the existing conditions these people have? *
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 16 people, 16.67%
- High Blood Pressure: 8 people, 8.33%
- Ovarian Cancer (cancer of ovary): 6 people, 6.25%
- Hyperthyroidism (over activity of the thyroid gland): 6 people, 6.25%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 6.25%
- Bone Disorder: 6 people, 6.25%
- Micturition Urgency (urgency to pass the urine): 5 people, 5.21%
- Carotid Artery Stenosis (narrowing of carotid artery): 5 people, 5.21%
- Back Pain: 5 people, 5.21%
- Asthma: 5 people, 5.21%
* Approximation only. Some reports may have incomplete information.
Do you take Alendronic acid and Fentanyl?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Alendronic acid (18,408 reports)
- Fentanyl (73,301 reports)
Browse all drug interactions of Alendronic acid and Fentanyl:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Alendronic acid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Fentanyl:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Alendronic acid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Fentanyl and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Stuckey BG, Sallie R, "Alendronate-induced unmasking or deterioration of coeliac disease: a case series", Osteoporosis International, 2015 Jan .
- Lee WY, Sun LM, Lin MC, Liang JA, Chang SN, Sung FC, Muo CH, Kao CH, "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", PloS one, 2012 Dec .
- Stuckey BG, Sallie R, "Alendronate-induced unmasking or deterioration of coeliac disease: a case series", Osteoporosis International, 2015 Jan .
- Lee WY, Sun LM, Lin MC, Liang JA, Chang SN, Sung FC, Muo CH, Kao CH, "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", PloS one, 2012 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on alendronate sodium and fentanyl citrate (the active ingredients of Alendronic acid and Fentanyl, respectively), and Alendronic acid and Fentanyl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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