Aleve and Mycophenolate mofetil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aleve (naproxen sodium) and Mycophenolate mofetil (mycophenolate mofetil). Common drug interactions include coma among females and blood pressure fluctuation among males.

The phase IV clinical study analyzes what interactions people have when they take Aleve and Mycophenolate mofetil. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Aleve?

Aleve has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 70,279 Aleve users. Check the latest studies of Aleve.

What is Mycophenolate mofetil?

Mycophenolate mofetil has active ingredients of mycophenolate mofetil. It is often used in myasthenia gravis. eHealthMe is studying from 93,460 Mycophenolate mofetil users. Check the latest studies of Mycophenolate mofetil.



On Jul, 07, 2026

35 people who take Aleve and Mycophenolate mofetil together, and have interactions are studied.

Aleve and Mycophenolate mofetil drug interactions.

What are the common drug interactions of Aleve and Mycophenolate Mofetil, by gender? *:

female:

  1. Coma (state of unconsciousness lasting more than six hours)
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Drug ineffective
  6. Blood pressure decreased
  7. Blood pressure increased
  8. Concussion (short loss of normal brain function in response to a head injury)
  9. Nasopharyngitis (inflammation of the nasopharynx)
  10. Renal failure (kidney dysfunction)

male:

  1. Blood pressure fluctuation
  2. Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters)
  3. Abdominal distension
  4. Asthenia (weakness)
  5. Blindness transient (sudden loss of vision)
  6. Blood pressure decreased
  7. Bone loss
  8. Cataract (clouding of the lens inside the eye)
  9. Constipation
  10. Cough

What are the common drug interactions of Aleve and Mycophenolate Mofetil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Eye discharge
  2. Eye irritation

30-39:

  1. Bone loss
  2. Cataract (clouding of the lens inside the eye)
  3. Cystitis (inflammation of the wall of the bladder)
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Gastrointestinal infection (infection of stomach and intestine)
  6. Ill-defined disorder
  7. Lower limb fracture
  8. Multiple fractures
  9. Osteoporosis (bones weak and more likely to break)
  10. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)

40-49:

  1. Blood pressure decreased
  2. Blood pressure increased
  3. Concussion (short loss of normal brain function in response to a head injury)
  4. Nasopharyngitis (inflammation of the nasopharynx)
  5. Hypersensitivity
  6. Seasonal allergy (allergic condition due to certain season)
  7. Skin exfoliation (removal of the oldest dead skin cells)
  8. Skin infection

50-59:

  1. Chronic kidney disease
  2. Dyspnoea (difficult or laboured respiration)
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Renal failure (kidney dysfunction)
  5. Respiratory tract infection

60+:

  1. Blood pressure fluctuation
  2. Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters)
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Body temperature decreased
  5. Mouth ulceration (mouth ulcers)
  6. Drug ineffective
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Choking sensation (feeling of obstruction in respiratory system)
  9. Dysphagia (a condition in which swallowing is difficult or painful)
  10. Blood glucose increased

What are the existing conditions these people have? *

  1. Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters): 13 people, 37.14%
  2. Insomnia (sleeplessness): 2 people, 5.71%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Aleve and Mycophenolate mofetil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Aleve:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Mycophenolate mofetil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aleve and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mycophenolate mofetil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on naproxen sodium and mycophenolate mofetil (the active ingredients of Aleve and Mycophenolate mofetil, respectively), and Aleve and Mycophenolate mofetil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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