Aleve and Vitamin b2 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aleve (naproxen sodium) and Vitamin b2 (riboflavin). Common drug interactions include anxiety among females and gastric cancer among males.

The phase IV clinical study analyzes what interactions people have when they take Aleve and Vitamin b2. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Aleve?

Aleve has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 70,279 Aleve users. Check the latest studies of Aleve.

What is Vitamin b2?

Vitamin b2 has active ingredients of riboflavin. It is often used in migraine. eHealthMe is studying from 1,740 Vitamin b2 users. Check the latest studies of Vitamin b2.

On Jul, 05, 2026

36 people who take Aleve and Vitamin b2 together, and have interactions are studied.

What are the common drug interactions of Aleve and Vitamin B2, by gender? *:

female:

Anxiety
Balance disorder
Dyspnoea (difficult or laboured respiration)
Lip dry
Neuralgia (pain in one or more nerves)
Tremor (trembling or shaking movements in one or more parts of your body)
Constipation
Drug ineffective
Feeling of body temperature change
Hot flush (sudden feelings of heat)

male:

Gastric cancer (stomach cancer)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

What are the common drug interactions of Aleve and Vitamin B2, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Enuresis (repeated inability to control urination)
Hospitalisation

20-29:

Anxiety
Arthralgia (joint pain)
Ear pain
Eye pain
Eye pruritus (eye itching)
Facial pain
Immune system disorder
Neuralgia (pain in one or more nerves)
Oral herpes (viral infection of mouth)
Rash

30-39:

Abasia (inability to walk)
Abdominal discomfort
Abdominal pain
Anxiety
Application site erythema (redness of the skin at application site)
Application site inflammation
Application site pain
Application site reaction
Application site vesicles (small bubble within a cell at application site)
Application site warmth

40-49:

Abdominal discomfort
Abdominal pain upper
Dizziness
Fatigue (feeling of tiredness)
Lip dry
Pruritus (severe itching of the skin)
Drug hypersensitivity
Lip swelling
Swollen tongue (swelling of tongue)

50-59:

Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)
Micturition urgency (urgency to pass the urine)
Mobility decreased (ability to move is reduced)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Neck pain
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Neuropathy peripheral (surface nerve damage)
Nystagmus (a condition of involuntary eye movement)

60+:

Nausea (feeling of having an urge to vomit)
Visual impairment
Gastric cancer (stomach cancer)
Panic reaction
Renal failure (kidney dysfunction)
Anxiety
Arthralgia (joint pain)
Back pain
Bursa disorder
Chills (felling of cold)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 19.44%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 16.67%
Headache (pain in head): 5 people, 13.89%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 11.11%
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 3 people, 8.33%
Vitamin D Decreased: 2 people, 5.56%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 5.56%
Depression: 2 people, 5.56%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 2 people, 5.56%
High Blood Pressure: 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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