Alfenta and Versed drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alfenta (alfentanil hydrochloride) and Versed (midazolam hydrochloride). Common drug interactions include anaphylactic shock among females and myalgia among males.

The phase IV clinical study analyzes what interactions people have when they take Alfenta and Versed. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Alfenta?

Alfenta has active ingredients of alfentanil hydrochloride. eHealthMe is studying from 1,508 Alfenta users. Check the latest studies of Alfenta.

What is Versed?

Versed has active ingredients of midazolam hydrochloride. It is often used in sedation during medical procedure. eHealthMe is studying from 6,869 Versed users. Check the latest studies of Versed.



On Jul, 11, 2026

13 people who take Alfenta and Versed together, and have interactions are studied.

Alfenta and Versed drug interactions.

What are the common drug interactions of Alfenta and Versed, by gender? *:

female:

  1. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
  2. Atrioventricular block complete (heart block complete)
  3. Axillary mass
  4. Cardiac arrest
  5. Chronic kidney disease
  6. Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
  7. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  8. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  9. Laryngospasm (an uncontrolled/involuntary muscular contraction of larynx)
  10. Muscle tightness

male:

  1. Myalgia (muscle pain)
  2. Aggression
  3. Paralysis
  4. Agitation (state of anxiety or nervous excitement)
  5. Arthralgia (joint pain)
  6. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  7. Loss of consciousness
  8. Monoparesis (one limb is very weak, but not completely paralyzed)
  9. Neuromuscular block prolonged
  10. Pain

What are the common drug interactions of Alfenta and Versed, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Axillary mass
  2. Muscle tightness
  3. Pain
  4. Pain in jaw

30-39:

  1. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  2. Neuromuscular block prolonged

40-49:

  1. Cardiac arrest
  2. Pulmonary oedema (fluid accumulation in the lungs)

50-59:

n/a

60+:

  1. Aggression
  2. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  3. Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
  4. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  5. Laryngospasm (an uncontrolled/involuntary muscular contraction of larynx)
  6. Monoparesis (one limb is very weak, but not completely paralyzed)
  7. Pain
  8. Pain in extremity
  9. Paralysis
  10. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. Sinusitis (inflammation of sinus): 1 person, 7.69%
  2. Lower Respiratory Tract Infection: 1 person, 7.69%
  3. High Blood Pressure: 1 person, 7.69%
  4. Headache (pain in head): 1 person, 7.69%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Alfenta and Versed?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Alfenta and Versed:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Alfenta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Versed:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alfenta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Versed and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on alfentanil hydrochloride and midazolam hydrochloride (the active ingredients of Alfenta and Versed, respectively), and Alfenta and Versed (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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