Alkeran and Cosopt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alkeran (melphalan) and Cosopt (dorzolamide hydrochloride; timolol maleate). Common drug interactions include anxiety among females and thrombosis among males.

The phase IV clinical study analyzes what interactions people have when they take Alkeran and Cosopt. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Alkeran?

Alkeran has active ingredients of melphalan. eHealthMe is studying from 5,429 Alkeran users. Check the latest studies of Alkeran.

What is Cosopt?

Cosopt has active ingredients of dorzolamide hydrochloride; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 9,029 Cosopt users. Check the latest studies of Cosopt.

On Jul, 27, 2026

15 people who take Alkeran and Cosopt together, and have interactions are studied.

What are the common drug interactions of Alkeran and Cosopt, by gender? *:

female:

Anxiety
Osteopenia (a condition where bone mineral density is lower than normal)
Pain
Spinal osteoarthritis (joint cartilage loss in spine)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Urinary tract infection
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Chest pain
Constipation
Diarrhoea

male:

Thrombosis (formation of a blood clot inside a blood vessel)

What are the common drug interactions of Alkeran and Cosopt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Actinic keratosis (skin disease due to sun exposure)
Aggression
Alopecia (absence of hair from areas of the body)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Aortic valve incompetence
Arrhythmia (irregular heartbeat)

50-59:

n/a

60+:

Anxiety
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Pain
Spinal osteoarthritis (joint cartilage loss in spine)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Urinary tract infection
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Chest pain
Constipation
Diarrhoea

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 14 people, 93.33%
Osteoporosis (bones weak and more likely to break): 4 people, 26.67%
Indigestion: 4 people, 26.67%
Fever: 4 people, 26.67%
Anaemia (lack of blood): 4 people, 26.67%
Metastases To Bone (cancer spreads to bone): 1 person, 6.67%
Depression: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Alkeran and Cosopt?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously