Alkeran and Phenergan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alkeran (melphalan) and Phenergan (promethazine hydrochloride). Common drug interactions include renal failure among females and agranulocytosis among males.

The phase IV clinical study analyzes what interactions people have when they take Alkeran and Phenergan. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Alkeran?

Alkeran has active ingredients of melphalan. eHealthMe is studying from 5,429 Alkeran users. Check the latest studies of Alkeran.

What is Phenergan?

Phenergan has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 25,312 Phenergan users. Check the latest studies of Phenergan.

On Jul, 09, 2026

36 people who take Alkeran and Phenergan together, and have interactions are studied.

Alkeran and Phenergan drug interactions.

What are the common drug interactions of Alkeran and Phenergan, by gender? *:

female:

Renal failure (kidney dysfunction)
Neck pain
Neuropathy peripheral (surface nerve damage)
Osteolysis (dissolution of bone)
Osteopenia (a condition where bone mineral density is lower than normal)
Anxiety
Dehydration (dryness resulting from the removal of water)
Pain in extremity
Pneumonia
Arthralgia (joint pain)

male:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Blood glucose fluctuation
Blood phosphorus decreased
Bone disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cataract (clouding of the lens inside the eye)
Cellulitis (infection under the skin)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

What are the common drug interactions of Alkeran and Phenergan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain
Anxiety
Back pain
Blood alkaline phosphatase increased
Blood glucose increased
Blood urea increased
Death
Diarrhoea
Nervousness
Renal pain (kidney pain)

40-49:

Asthma
Anxiety
Arthralgia (joint pain)
Asthenia (weakness)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Back pain
Blood alkaline phosphatase increased
Blood creatinine increased
Chest pain
Compression fracture (fracture due to pressure caused by injury)

50-59:

Anaemia (lack of blood)
Anxiety
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Aphthous stomatitis (mouth ulcer)
Arteriosclerosis (thickening and hardening of arteries)
Asthma
Back pain
Blood creatine phosphokinase increased
Blood creatine phosphokinase mb increased
Blood glucose fluctuation

60+:

Anaemia (lack of blood)
Cataract (clouding of the lens inside the eye)
Multi-organ failure (multisystem organ failure)
Multiple myeloma (cancer of the plasma cells)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Osteonecrosis of jaw (death of bone of jaw)
Pleural effusion (water on the lungs)
Pneumonia
Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 9 people, 25.00%
Osteolysis (dissolution of bone): 2 people, 5.56%
High Blood Cholesterol: 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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