Allopurinol and Definity drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Allopurinol (allopurinol) and Definity (perflutren). Common drug interactions include respiration among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Allopurinol and Definity. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Allopurinol?

Allopurinol has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,869 Allopurinol users. Check the latest studies of Allopurinol.

What is Definity?

Definity has active ingredients of perflutren. eHealthMe is studying from 4,853 Definity users. Check the latest studies of Definity.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

50 people who take Allopurinol and Definity together, and have interactions are studied.

Allopurinol and Definity drug interactions.

What are the common drug interactions of Allopurinol and Definity, by gender? *:

female:

Respiration (transport of oxygen from the outside air to the cells within tissues)
Sensation of pressure
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Throat tightness
Tremor (trembling or shaking movements in one or more parts of your body)
Urticaria (rash of round, red welts on the skin that itch intensely)
Vomiting
Back pain
Dizziness
Dyspnoea (difficult or laboured respiration)

male:

Back pain
Muscle spasms (muscle contraction)
Hyperhidrosis (abnormally increased sweating)
Pain
Hypersensitivity
Anaphylactic reaction (serious allergic reaction)
Blood pressure increased
Chest pain
Death
Dysgeusia (disorder of the sense of taste)

What are the common drug interactions of Allopurinol and Definity, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hypoaesthesia (reduced sense of touch or sensation)

40-49:

Back pain
Muscle spasms (muscle contraction)

50-59:

Throat tightness
Urticaria (rash of round, red welts on the skin that itch intensely)
Asthenia (weakness)
Back pain
Flushing (the warm, red condition of human skin)
Hypotension (abnormally low blood pressure)
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Rash generalised (rash on most of body parts)
Muscle spasms (muscle contraction)

60+:

Back pain
Dizziness
Retching (strong involuntary effort to vomit)
Tremor (trembling or shaking movements in one or more parts of your body)
Anaphylactic reaction (serious allergic reaction)
Bladder pain
Cellulitis (infection under the skin)
Dysgeusia (disorder of the sense of taste)
Feeling hot
Headache (pain in head)

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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