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Allopurinol and Xofigo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Allopurinol (allopurinol) and Xofigo (radium ra-223 dichloride). Common drug interactions include pancytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Allopurinol and Xofigo. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Allopurinol?

Allopurinol has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,868 Allopurinol users. Check the latest studies of Allopurinol.

What is Xofigo?

Xofigo has active ingredients of radium ra-223 dichloride. eHealthMe is studying from 4,948 Xofigo users. Check the latest studies of Xofigo.

On Aug, 11, 2026

24 people who take Allopurinol and Xofigo together, and have interactions are studied.

Allopurinol and Xofigo drug interactions.

What are the common drug interactions of Allopurinol and Xofigo, by gender? *:

female:

n/a

male:

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  2. Anaemia (lack of blood)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Rash
  5. Headache (pain in head)
  6. Nausea (feeling of having an urge to vomit)
  7. Pain
  8. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  9. Fall
  10. Leukopenia (less number of white blood cells in blood)

What are the common drug interactions of Allopurinol and Xofigo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  2. Asthenia (weakness)
  3. Leukopenia (less number of white blood cells in blood)
  4. Lymphadenopathy (disease or enlargement of lymph nodes)
  5. Metastases to liver (cancer spreads to liver)
  6. Metastases to lung (cancer spreads to lung)
  7. Platelet count decreased
  8. Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
  9. Subdural haematoma (blood collects between the skull and the surface of the brain)
  10. Thrombocytopenia (decrease of platelets in blood)

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 10 people, 41.67%
  2. Prostate Cancer: 9 people, 37.50%
  3. Prostate Cancer Stage Iv: 7 people, 29.17%
  4. Depression: 3 people, 12.50%
  5. Bone Pain: 3 people, 12.50%
  6. Prostate Cancer Metastatic: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Allopurinol and Xofigo?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Allopurinol and Xofigo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Allopurinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Xofigo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Allopurinol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xofigo and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol and radium ra-223 dichloride (the active ingredients of Allopurinol and Xofigo, respectively), and Allopurinol and Xofigo (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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