Aloe and Senna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aloe (aloe) and Senna (senna). Common drug interactions include haematochezia among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Aloe and Senna. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Aloe?

Aloe has active ingredients of aloe. eHealthMe is studying from 2,128 Aloe users. Check the latest studies of Aloe.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

On Jul, 21, 2026

50 people who take Aloe and Senna together, and have interactions are studied.

What are the common drug interactions of Aloe and Senna, by gender? *:

female:

Haematochezia (passage of stools containing blood)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Melaena (the passage of black, tarry stools)
Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)
Palpitations (feelings or sensations that your heart is pounding or racing)
Rectal haemorrhage (bleeding from anus)
Cardiac arrest
Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)

male:

Back pain
Abdominal pain
Alanine aminotransferase increased
Anaemia (lack of blood)
Aspartate aminotransferase increased
Blood lactate dehydrogenase increased
Cough
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Drug ineffective

What are the common drug interactions of Aloe and Senna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Agitation (state of anxiety or nervous excitement)
Eye swelling
Intentional self-injury

40-49:

Disease progression
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Lung neoplasm malignant (cancer tumour of lung)

50-59:

Amylase decreased
Aspartate aminotransferase increased
Asthenia (weakness)
Basophil percentage increased
Blood albumin decreased
Blood alkaline phosphatase increased
Blood calcium decreased
Blood chromogranin a increased
Blood glucose decreased
Blood glucose increased

60+:

Back pain
Contusion (a type of hematoma of tissue in which capillaries)
Hypertension (high blood pressure)
Inflammatory bowel disease
Mesenteric artery stenosis (narrowing of the arteries supplying blood to the intestines)
Pleural effusion (water on the lungs)
Road traffic accident
Traumatic fracture (a fracture due to sustained trauma)
Abdominal pain
Abdominal pain upper

What are the existing conditions these people have? *

Pain: 9 people, 18.00%
Multiple Myeloma (cancer of the plasma cells): 9 people, 18.00%
Primary Myelofibrosis (primary disorder of the bone marrow): 6 people, 12.00%
Renal Cell Carcinoma (a kidney cancer): 5 people, 10.00%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 8.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 8.00%
Parkinson's Disease: 3 people, 6.00%
Fever: 3 people, 6.00%
Cough: 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

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