Alogliptin and Apixaban drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Alogliptin (alogliptin benzoate) and Apixaban (apixaban). Common drug interactions include bradycardia among females and hyperkalaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Alogliptin and Apixaban. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.
What is Alogliptin?
Alogliptin has active ingredients of alogliptin benzoate. eHealthMe is studying from 1,943 Alogliptin users. Check the latest studies of Alogliptin.
What is Apixaban?
Apixaban has active ingredients of apixaban. It is often used in blood clots. eHealthMe is studying from 60,351 Apixaban users. Check the latest studies of Apixaban.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
57 people who take Alogliptin and Apixaban together, and have interactions are studied.

What are the common drug interactions of Alogliptin and Apixaban, by gender? *:
female:
- Bradycardia (abnormally slow heart action)
- Cardiac arrest
- Cellulitis (infection under the skin)
- Hyperkalaemia (damage to or disease of the kidney)
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
- Blood glucose increased
- Gout (uric acid crystals building up in the body)
- Malaise (a feeling of general discomfort or uneasiness)
- Tumour haemorrhage (bleeding from tumour)
- Thrombocytopenia (decrease of platelets in blood)
male:
- Hyperkalaemia (damage to or disease of the kidney)
- Circulatory collapse
- Cardiac failure
- Chest pain
- Chronic kidney disease
- Diabetic foot
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Drug ineffective
- Dyspnoea (difficult or laboured respiration)
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
What are the common drug interactions of Alogliptin and Apixaban, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Thrombocytopenia (decrease of platelets in blood)
60+:
- Hyperkalaemia (damage to or disease of the kidney)
- Bradycardia (abnormally slow heart action)
- Colon cancer
- Retinal haemorrhage (bleeding from retina)
- Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)
- Vitreous haemorrhage (intraocular (inside the eye) bleeding)
- Abnormal loss of weight
- Cardiac failure
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Chest pain
What are the existing conditions these people have? *
- Type 2 Diabetes: 14 people, 24.56%
- High Blood Pressure: 9 people, 15.79%
- Diabetes: 6 people, 10.53%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 10.53%
- Primary Myelofibrosis (primary disorder of the bone marrow): 5 people, 8.77%
- Spinal Compression Fracture (fracture due to spinal compression on bone): 4 people, 7.02%
- Rickets (softening of bones): 4 people, 7.02%
- Iron Deficiency Anaemia: 4 people, 7.02%
- Gout (uric acid crystals building up in the body): 4 people, 7.02%
- Erection Problems: 4 people, 7.02%
* Approximation only. Some reports may have incomplete information.
Do you take Alogliptin and Apixaban?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Alogliptin (1,943 reports)
- Apixaban (60,351 reports)
Browse all drug interactions of Alogliptin and Apixaban:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Alogliptin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Apixaban:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Alogliptin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Apixaban and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on alogliptin benzoate and apixaban (the active ingredients of Alogliptin and Apixaban, respectively), and Alogliptin and Apixaban (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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