Alphagan p and Rhopressa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alphagan p (brimonidine tartrate) and Rhopressa (netarsudil dimesylate). Common drug interactions include eye pain among females and vision blurred among males.

The phase IV clinical study analyzes what interactions people have when they take Alphagan p and Rhopressa. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.

What is Alphagan p?

Alphagan p has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 6,579 Alphagan p users. Check the latest studies of Alphagan p.

What is Rhopressa?

Rhopressa has active ingredients of netarsudil dimesylate. eHealthMe is studying from 1,512 Rhopressa users. Check the latest studies of Rhopressa.

On Aug, 04, 2026

70 people who take Alphagan p and Rhopressa together, and have interactions are studied.

Alphagan p and Rhopressa drug interactions.

What are the common drug interactions of Alphagan P and Rhopressa, by gender? *:

female:

Eye pain
Conjunctival hyperaemia (congestion of conjunctival vessels)
Blood pressure increased
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Vision blurred
Bacterial infection
Chills (felling of cold)
Infusion related reaction
Kidney infection

male:

Vision blurred
Conjunctival hyperaemia (congestion of conjunctival vessels)
Dehydration (dryness resulting from the removal of water)
Depression
Fatigue (feeling of tiredness)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Hyphaema (collection of blood inside the front part of the eye)
Lethargy (tiredness)

What are the common drug interactions of Alphagan P and Rhopressa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dehydration (dryness resulting from the removal of water)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Pain
Psoriasis (immune-mediated disease that affects the skin)
Syncope (loss of consciousness with an inability to maintain postural tone)
Vitamin d deficiency

40-49:

Conjunctival hyperaemia (congestion of conjunctival vessels)
Eye inflammation
Instillation site erythema (instillation site redness)
Muscle spasms (muscle contraction)
Pain
Pain in extremity

50-59:

Neurosarcoidosis (a condition of unknown cause featuring a collection of immune cells in various tissues, involving the central nervous system (brain and spinal cord))
Retinal artery occlusion (blockage of retinal artery)

60+:

Vision blurred
Eye pain
Intraocular pressure increased
Lacrimation increased
Limb discomfort (discomfort in leg)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Peripheral coldness
Retinal vascular thrombosis (clot formation in small veins that carry blood away from the retina)
Instillation site pain
Acne (skin problems that cause pimples)

What are the existing conditions these people have? *

Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 9 people, 12.86%
Immunodeficiency Common Variable: 6 people, 8.57%
Multiple Myeloma (cancer of the plasma cells): 5 people, 7.14%
High Blood Pressure: 5 people, 7.14%
Intraocular Pressure Increased: 4 people, 5.71%
Dry Eyes (lack of adequate tears): 4 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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