Alphagan p and Zometa drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Alphagan p (brimonidine tartrate) and Zometa (zoledronic acid). Common drug interactions include anaemia among females and osteoarthritis among males.
The phase IV clinical study analyzes what interactions people have when they take Alphagan p and Zometa. It is created by eHealthMe based on reports of 88 people who take the same drugs from the FDA, and is updated regularly.
What is Alphagan p?
Alphagan p has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 6,579 Alphagan p users. Check the latest studies of Alphagan p.
What is Zometa?
Zometa has active ingredients of zoledronic acid. It is often used in multiple myeloma. eHealthMe is studying from 71,434 Zometa users. Check the latest studies of Zometa.
88 people who take Alphagan p and Zometa together, and have interactions are studied.

What are the common drug interactions of Alphagan P and Zometa, by gender? *:
female:
- Anaemia (lack of blood)
- Toothache (tooth pain)
- Osteonecrosis of jaw (death of bone of jaw)
- Atelectasis (partial or complete collapse of the lung)
- Spinal column injury (spinal cord bone injury)
- Pleural effusion (water on the lungs)
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Hypoaesthesia (reduced sense of touch or sensation)
- Oedema peripheral (superficial swelling)
- Hypokalaemia (low potassium)
male:
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Metastases to bone (cancer spreads to bone)
- Pain
- Abscess (pus)
- Activities of daily living impaired
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Arrhythmia (irregular heartbeat)
- Arteriosclerosis (thickening and hardening of arteries)
- Back pain
What are the common drug interactions of Alphagan P and Zometa, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Abscess (pus)
- Activities of daily living impaired
- Agitation (state of anxiety or nervous excitement)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Arrhythmia (irregular heartbeat)
- Arteriosclerosis (thickening and hardening of arteries)
- Arthropathy
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Back pain
40-49:
n/a
50-59:
- Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
- Pain
- Abdominal pain
- Abdominal pain upper
- Alpha haemolytic streptococcal infection (infections with alpha-haemolytic strep bacteria are common; many strains live naturally in humans)
- Anxiety
- Atelectasis (partial or complete collapse of the lung)
- Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
- Carotid bruit (sound heard over the carotid artery area during auscultation)
- Cholecystitis (infection of gallbladder)
60+:
- Anxiety
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Pneumonia
- Osteomyelitis (infection of bone)
- Pain in extremity
- Renal cyst (kidney cyst)
- Visual impairment
- Toothache (tooth pain)
- Confusional state
What are the existing conditions these people have? *
- Muscle Spasms (muscle contraction): 12 people, 13.64%
- Toothaches (tooth pain): 11 people, 12.50%
- Constipation: 9 people, 10.23%
- Neuralgia (pain in one or more nerves): 6 people, 6.82%
- High Blood Pressure: 6 people, 6.82%
- Diabetes: 6 people, 6.82%
- Back Pain: 6 people, 6.82%
- Abdominal Pain Upper: 6 people, 6.82%
- Prostate Cancer: 5 people, 5.68%
- Metastases To Bone (cancer spreads to bone): 5 people, 5.68%
* Approximation only. Some reports may have incomplete information.
Do you take Alphagan p and Zometa?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Alphagan p (6,579 reports)
- Zometa (71,434 reports)
Browse all drug interactions of Alphagan p and Zometa:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Alphagan p:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zometa:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Alphagan p and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zometa and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on brimonidine tartrate and zoledronic acid (the active ingredients of Alphagan p and Zometa, respectively), and Alphagan p and Zometa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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