Alphagan and Bactroban drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alphagan (brimonidine tartrate) and Bactroban (mupirocin). Common drug interactions include hyperaesthesia among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Alphagan and Bactroban. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Alphagan?

Alphagan has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 9,981 Alphagan users. Check the latest studies of Alphagan.

What is Bactroban?

Bactroban has active ingredients of mupirocin. It is often used in infection. eHealthMe is studying from 4,967 Bactroban users. Check the latest studies of Bactroban.



On Jul, 13, 2026

29 people who take Alphagan and Bactroban together, and have interactions are studied.

Alphagan and Bactroban drug interactions.

What are the common drug interactions of Alphagan and Bactroban, by gender? *:

female:

  1. Hyperaesthesia
  2. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  3. Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
  4. Spinal compression fracture (fracture due to spinal compression on bone)
  5. Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
  6. Postoperative wound infection
  7. Procedural complication
  8. Spinal osteoarthritis (joint cartilage loss in spine)
  9. Arthralgia (joint pain)
  10. Back pain

male:

  1. Drug ineffective
  2. Anaemia (lack of blood)
  3. Death
  4. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  5. Peripheral swelling
  6. White blood cell count decreased
  7. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  8. Pneumonia
  9. Pyrexia (fever)
  10. Angina pectoris (chest pain due to ischemia of the heart muscle)

What are the common drug interactions of Alphagan and Bactroban, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Iritis (painful inflammation of the iris of the eye)
  2. Retinal tear
  3. Sneezing
  4. Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
  5. Inner ear disorder
  6. Visual impairment
  7. Joint swelling
  8. Pain
  9. Visual acuity reduced (reduced clearness of vision)
  10. Arthralgia (joint pain)

60+:

  1. Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
  2. Postoperative wound infection
  3. Scoliosis (a medical condition in which a person's spine is curved from side to side)
  4. Spinal fracture (fracture in one of vertebrae)
  5. Wound dehiscence (a surgical incision reopens either internally or externally)
  6. Abnormal behaviour
  7. Apnoea (suspension of external breathing)
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  9. Atelectasis (partial or complete collapse of the lung)
  10. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the existing conditions these people have? *

  1. Pain: 10 people, 34.48%
  2. Muscle Spasms (muscle contraction): 6 people, 20.69%
  3. Multiple Myeloma (cancer of the plasma cells): 5 people, 17.24%
  4. Uveitis (inflammation of the uvea): 3 people, 10.34%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 10.34%
  6. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 10.34%
  7. Cough: 3 people, 10.34%
  8. Fungal Skin Infection: 3 people, 10.34%
  9. Gastric Disorder (disease of stomach): 3 people, 10.34%
  10. Hypersensitivity: 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Alphagan and Bactroban:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Alphagan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Bactroban:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alphagan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bactroban and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on brimonidine tartrate and mupirocin (the active ingredients of Alphagan and Bactroban, respectively), and Alphagan and Bactroban (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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