Alphagan and Colcrys drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Alphagan (brimonidine tartrate) and Colcrys (colchicine). Common drug interactions include chronic kidney disease among females and eye infection among males.
The phase IV clinical study analyzes what interactions people have when they take Alphagan and Colcrys. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Alphagan?
Alphagan has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 9,981 Alphagan users. Check the latest studies of Alphagan.
What is Colcrys?
Colcrys has active ingredients of colchicine. It is often used in gout. eHealthMe is studying from 4,546 Colcrys users. Check the latest studies of Colcrys.
14 people who take Alphagan and Colcrys together, and have interactions are studied.

What are the common drug interactions of Alphagan and Colcrys, by gender? *:
female:
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Abnormal behaviour
- Bradycardia (abnormally slow heart action)
- Drug ineffective
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
male:
- Eye infection
- Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
- Muscle spasms (muscle contraction)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Back pain
- Cardiac disorder
- Cardiac failure congestive
- Chronic kidney disease
- Constipation
What are the common drug interactions of Alphagan and Colcrys, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Fatigue (feeling of tiredness)
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Muscle spasms (muscle contraction)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Renal failure (kidney dysfunction)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Abnormal behaviour
- Back pain
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 35.71%
- High Blood Pressure: 5 people, 35.71%
- Pain: 4 people, 28.57%
- High Blood Cholesterol: 3 people, 21.43%
- Thyroid Diseases: 2 people, 14.29%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 14.29%
- Cough: 2 people, 14.29%
- Diabetes: 2 people, 14.29%
- Eye Infection: 2 people, 14.29%
- Eye Pain: 2 people, 14.29%
* Approximation only. Some reports may have incomplete information.
Do you take Alphagan and Colcrys?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Alphagan and Colcrys:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Alphagan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Colcrys:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Alphagan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Colcrys and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on brimonidine tartrate and colchicine (the active ingredients of Alphagan and Colcrys, respectively), and Alphagan and Colcrys (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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