Alphagan and Effexor xr drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alphagan (brimonidine tartrate) and Effexor xr (venlafaxine hydrochloride). Common drug interactions include drug ineffective among females and gastrointestinal infection among males.

The phase IV clinical study analyzes what interactions people have when they take Alphagan and Effexor xr. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Alphagan?

Alphagan has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 9,981 Alphagan users. Check the latest studies of Alphagan.

What is Effexor xr?

Effexor xr has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 35,233 Effexor xr users. Check the latest studies of Effexor xr.

On Jul, 31, 2026

32 people who take Alphagan and Effexor xr together, and have interactions are studied.

Alphagan and Effexor xr drug interactions.

What are the common drug interactions of Alphagan and Effexor Xr, by gender? *:

female:

Drug ineffective
Transplant
Constipation
Dry mouth
Dyspnoea (difficult or laboured respiration)
Hypertension (high blood pressure)
Insomnia (sleeplessness)
Intraocular pressure increased
Sepsis (a severe blood infection that can lead to organ failure and death)
Urinary tract infection

male:

Gastrointestinal infection (infection of stomach and intestine)
Fatigue (feeling of tiredness)
Cor pulmonale chronic (long lasting enlargement of the right ventricle of the heart)
Cough
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypertensive nephropathy (hypertensive renal disease)
Malaise (a feeling of general discomfort or uneasiness)
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Renal failure chronic (long lasting kidney dysfunction)

What are the common drug interactions of Alphagan and Effexor Xr, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Suicidal ideation
Vitreous haemorrhage (intraocular (inside the eye) bleeding)
Blindness unilateral
Body temperature increased
Chest pain
Cough
Dyspnoea (difficult or laboured respiration)
Hypertension (high blood pressure)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

50-59:

Intraocular pressure increased
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood cholesterol increased
Blood glucose increased
Blood triglycerides increased
Breast pain
Breast tenderness
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Disease recurrence
Fear

60+:

Drug ineffective
Gastrointestinal infection (infection of stomach and intestine)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypertensive nephropathy (hypertensive renal disease)
Malaise (a feeling of general discomfort or uneasiness)
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Renal failure chronic (long lasting kidney dysfunction)
Restless legs syndrome (a powerful urge to move your legs)
Rosacea (a skin condition that causes facial redness)

What are the existing conditions these people have? *

Asthma: 5 people, 15.62%
Pain: 3 people, 9.38%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 6.25%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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