Alphagan and Ketoconazole drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Alphagan (brimonidine tartrate) and Ketoconazole (ketoconazole). Common drug interactions include back pain among females and back pain among males.
The phase IV clinical study analyzes what interactions people have when they take Alphagan and Ketoconazole. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.
What is Alphagan?
Alphagan has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 9,981 Alphagan users. Check the latest studies of Alphagan.
What is Ketoconazole?
Ketoconazole has active ingredients of ketoconazole. It is often used in fungal infection. eHealthMe is studying from 16,014 Ketoconazole users. Check the latest studies of Ketoconazole.
62 people who take Alphagan and Ketoconazole together, and have interactions are studied.

What are the common drug interactions of Alphagan and Ketoconazole, by gender? *:
female:
- Back pain
- Depression
- Dysphagia (a condition in which swallowing is difficult or painful)
- Insomnia (sleeplessness)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Osteolysis (dissolution of bone)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Pain in extremity
- Pain in jaw
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
male:
- Back pain
- Pain
- Swelling
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Deformity (disfigurement)
- Disability
- Injury
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Aortic dilatation
- Aortic valve incompetence
What are the common drug interactions of Alphagan and Ketoconazole, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Atelectasis (partial or complete collapse of the lung)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Back pain
- Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
- Bone fragmentation
- Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
- Bone pain
- Bullous lung disease
- Cardiac failure congestive
- Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)
50-59:
- Acute respiratory distress syndrome
- Acute respiratory failure
- Balance disorder
- Fall
- Pneumonia
- Pneumonia influenzal (the flu with pneumonia)
60+:
- Pain
- Swelling
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Depression
- Disability
- Injury
- Pain in extremity
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Skin discolouration (change of skin colour)
- Skin ulcer
What are the existing conditions these people have? *
- Stress And Anxiety: 13 people, 20.97%
- Anaemia (lack of blood): 8 people, 12.90%
- Depression: 8 people, 12.90%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 12.90%
- High Blood Pressure: 8 people, 12.90%
- High Blood Cholesterol: 7 people, 11.29%
- Metastases To Central Nervous System (cancer spreads to central nervous system): 7 people, 11.29%
- Insomnia (sleeplessness): 7 people, 11.29%
- Back Pain: 6 people, 9.68%
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 6 people, 9.68%
* Approximation only. Some reports may have incomplete information.
Do you take Alphagan and Ketoconazole?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Alphagan (9,981 reports)
- Ketoconazole (16,014 reports)
Browse all drug interactions of Alphagan and Ketoconazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Alphagan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ketoconazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Alphagan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ketoconazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on brimonidine tartrate and ketoconazole (the active ingredients of Alphagan and Ketoconazole, respectively), and Alphagan and Ketoconazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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