Alprazolam and Clexane drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alprazolam (alprazolam) and Clexane (enoxaparin sodium). Common drug interactions include colitis among females and alanine aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Alprazolam and Clexane. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Alprazolam?

Alprazolam has active ingredients of alprazolam. It is often used in stress and anxiety. eHealthMe is studying from 134,864 Alprazolam users. Check the latest studies of Alprazolam.

What is Clexane?

Clexane has active ingredients of enoxaparin sodium. eHealthMe is studying from 14,679 Clexane users. Check the latest studies of Clexane.



On Jun, 17, 2026

62 people who take Alprazolam and Clexane together, and have interactions are studied.

Alprazolam and Clexane drug interactions.

What are the common drug interactions of Alprazolam and Clexane, by gender? *:

female:

  1. Colitis (inflammation of colon)
  2. Intestinal obstruction
  3. Jugular vein thrombosis (clot in jugular vein)
  4. Sepsis (a severe blood infection that can lead to organ failure and death)
  5. Abdominal rigidity
  6. Dizziness
  7. Emotional distress
  8. Obstruction gastric (obstruction in stomach)
  9. Renal failure (kidney dysfunction)
  10. Respiratory distress (difficulty in breathing)

male:

  1. Alanine aminotransferase increased
  2. Hypertransaminasaemia
  3. Haematuria (presence of blood in urine)
  4. Blood creatinine increased
  5. Cholecystitis (infection of gallbladder)
  6. Colitis ulcerative (inflammation of colon with ulcer)
  7. Haemoglobin decreased
  8. Hallucination (an experience involving the perception of something not present)
  9. Neutropenia (an abnormally low number of neutrophils)
  10. Osteonecrosis of jaw (death of bone of jaw)

What are the common drug interactions of Alprazolam and Clexane, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Colitis ulcerative (inflammation of colon with ulcer)
  2. Haemoglobin decreased
  3. Post procedural haemorrhage (post procedural bleeding)

20-29:

n/a

30-39:

  1. Abdominal rigidity
  2. Chest pain
  3. Emotional distress
  4. Chest discomfort
  5. Dyspnoea (difficult or laboured respiration)
  6. Headache (pain in head)
  7. Tremor (trembling or shaking movements in one or more parts of your body)

40-49:

  1. Arrhythmia (irregular heartbeat)
  2. Cardiac failure
  3. Cardiomyopathy (weakening of the heart muscle)
  4. Diastolic dysfunction
  5. Ejection fraction decreased (systolic heart failure)
  6. Chest pain
  7. Jugular vein thrombosis (clot in jugular vein)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Blood creatinine increased
  10. Hyperkalaemia (damage to or disease of the kidney)

50-59:

  1. Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
  2. Pneumonia
  3. Colitis (inflammation of colon)
  4. Intestinal obstruction
  5. Cardiac tamponade (fluid accumulates in heart covering)
  6. Encephalopathy (functioning of the brain is affected by some agent or condition)
  7. Hepatic failure (liver failure)
  8. Myocarditis (inflammation of heart muscle myocardium)
  9. Renal failure (kidney dysfunction)
  10. Drug ineffective

60+:

  1. Alanine aminotransferase increased
  2. Hypertransaminasaemia
  3. Cholecystitis (infection of gallbladder)
  4. Haematuria (presence of blood in urine)
  5. Hallucination (an experience involving the perception of something not present)
  6. Hyperkalaemia (damage to or disease of the kidney)
  7. Peripheral swelling
  8. Productive cough
  9. Pyrexia (fever)
  10. Respiratory distress (difficulty in breathing)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 13 people, 20.97%
  2. High Blood Pressure: 12 people, 19.35%
  3. Insomnia (sleeplessness): 7 people, 11.29%
  4. Nausea (feeling of having an urge to vomit): 4 people, 6.45%
  5. Diabetes: 4 people, 6.45%
  6. Depression: 4 people, 6.45%
  7. Constipation: 4 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Alprazolam and Clexane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Alprazolam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Clexane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alprazolam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clexane and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on alprazolam and enoxaparin sodium (the active ingredients of Alprazolam and Clexane, respectively), and Alprazolam and Clexane (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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