Alprostadil and Cobamamide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Alprostadil (alprostadil) and Cobamamide (dibencozide). Common drug interactions include abdominal distension among females and blood urea increased among males.
The phase IV clinical study analyzes what interactions people have when they take Alprostadil and Cobamamide. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Alprostadil?
Alprostadil has active ingredients of alprostadil. It is often used in erection problems. eHealthMe is studying from 2,653 Alprostadil users. Check the latest studies of Alprostadil.
What is Cobamamide?
Cobamamide has active ingredients of dibencozide. eHealthMe is studying from 1,046 Cobamamide users. Check the latest studies of Cobamamide.
17 people who take Alprostadil and Cobamamide together, and have interactions are studied.

What are the common drug interactions of Alprostadil and Cobamamide, by gender? *:
female:
- Abdominal distension
- Anaemia (lack of blood)
- Bilirubin conjugated increased
- Blood glucose increased
- Blood urea increased
- Haemoglobin decreased
- Lymphocyte count decreased
- Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
- Pancreatitis (inflammation of pancreas)
- Platelet count decreased
male:
- Blood urea increased
- Haemoglobin decreased
- Bilirubin conjugated increased
- Blood cholesterol decreased
- Kidney transplant rejection
- Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues)
- Proteinuria (presence of protein in the urine)
- Renal failure (kidney dysfunction)
- Protein urine present
- Abdominal discomfort
What are the common drug interactions of Alprostadil and Cobamamide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Blood urea increased
- Haemoglobin decreased
- Glomerular filtration rate decreased
- Anaemia (lack of blood)
- Blood glucose increased
- Incision site pain
- Lymphocyte count decreased
- Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
- Urinary tract infection
- Abdominal distension
40-49:
- Lymphocyte count decreased
- Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
- Pancreatitis (inflammation of pancreas)
- Platelet count decreased
- White blood cell count increased
- Abdominal distension
- Anaemia (lack of blood)
- Bilirubin conjugated increased
- Blood glucose increased
- Blood urea increased
50-59:
- Meningitis cryptococcal (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
60+:
- Lung infection
- Plasma cell myeloma (cancer that begins in plasma cells)
- Chronic kidney disease
What are the existing conditions these people have? *
- Anaemia (lack of blood): 14 people, 82.35%
- High Blood Pressure: 14 people, 82.35%
- Urination - Excessive Volume: 10 people, 58.82%
- Red Blood Cell Count Decreased: 10 people, 58.82%
- Vasospasm (sudden constriction of a blood vessel, reducing its diameter and flow rate): 10 people, 58.82%
- Heart Disease: 8 people, 47.06%
- Hypotension (abnormally low blood pressure): 8 people, 47.06%
- Lipids Increased (excess lipid in body): 8 people, 47.06%
- Diarrhea: 6 people, 35.29%
- Haemostasis (stopping of bleeding): 6 people, 35.29%
* Approximation only. Some reports may have incomplete information.
Do you take Alprostadil and Cobamamide?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Alprostadil (2,653 reports)
- Cobamamide (1,046 reports)
Browse all drug interactions of Alprostadil and Cobamamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Alprostadil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cobamamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Alprostadil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cobamamide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on alprostadil and dibencozide (the active ingredients of Alprostadil and Cobamamide, respectively), and Alprostadil and Cobamamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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