Ambien and Lithobid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ambien (zolpidem tartrate) and Lithobid (lithium carbonate). Common drug interactions include appendicitis among females and suicide attempt among males.

The phase IV clinical study analyzes what interactions people have when they take Ambien and Lithobid. It is created by eHealthMe based on reports of 95 people who take the same drugs from the FDA, and is updated regularly.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

What is Lithobid?

Lithobid has active ingredients of lithium carbonate. It is often used in bipolar disorder. eHealthMe is studying from 1,281 Lithobid users. Check the latest studies of Lithobid.

On Jul, 15, 2026

95 people who take Ambien and Lithobid together, and have interactions are studied.

What are the common drug interactions of Ambien and Lithobid, by gender? *:

female:

Appendicitis (inflammation of the appendix)
Back pain
Bartholin's abscess (infection of one or both of the two bartholin's glands, which are located one on either side of the opening of the vagina)
Bartholin's cyst (cyst is formed on one or both of the two bartholin's glands, which are located one on either side of the opening of the vagina)
Breast pain
Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
Cervix carcinoma stage 0 (abnormal cells are found in the innermost lining of the cervix. these abnormal cells may become cancer and spread into nearby normal tissue)
Chest discomfort
Confusional state
Diplopia (double vision)

male:

Suicide attempt
Suicidal ideation
Erectile dysfunction
Weight increased
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Alcohol abuse
Anxiety
Asthma exercise induced
Blood pressure increased
Drug abuser

What are the common drug interactions of Ambien and Lithobid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Overdose
Suicide attempt

20-29:

Suicidal ideation
Weight increased
Abdominal pain
Abdominal pain upper
Anger
Appendicitis (inflammation of the appendix)
Asthenia (weakness)
Back pain
Bartholin's abscess (infection of one or both of the two bartholin's glands, which are located one on either side of the opening of the vagina)
Bartholin's cyst (cyst is formed on one or both of the two bartholin's glands, which are located one on either side of the opening of the vagina)

30-39:

Anaphylactic reaction (serious allergic reaction)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Hypotension (abnormally low blood pressure)
Respiratory distress (difficulty in breathing)
Scoliosis (a medical condition in which a person's spine is curved from side to side)
Blood cholesterol increased
Blood triglycerides increased
Clumsiness (a lack of coordination or elegance)

40-49:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Asthenia (weakness)
Back injury
Blood cholesterol increased
Blood triglycerides increased
Colon gangrene (colon tissue dies)
Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels)
Cyst (a closed sac)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Drooling (drop saliva uncontrollably from the mouth)

50-59:

Constipation
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug abuser
Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Memory impairment
Sinusitis (inflammation of sinus)
Somnolence (a state of near-sleep, a strong desire for sleep)
Vision blurred
Aggression

60+:

Bradycardia (abnormally slow heart action)
Drug ineffective
Face oedema (swelling of face)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Stress And Anxiety: 26 people, 27.37%
Sleep Disorder: 21 people, 22.11%
Depression: 13 people, 13.68%
Headache (pain in head): 12 people, 12.63%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 6 people, 6.32%
Pain: 5 people, 5.26%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 5 people, 5.26%
Mania (a state of abnormally elevated or irritable mood): 5 people, 5.26%
Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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