Ambien and Menest drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ambien (zolpidem tartrate) and Menest (estrogens, esterified). Common drug interactions include acne among females.

The phase IV clinical study analyzes what interactions people have when they take Ambien and Menest. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

What is Menest?

Menest has active ingredients of estrogens, esterified. It is often used in hormone replacement therapy. eHealthMe is studying from 843 Menest users. Check the latest studies of Menest.



On Jul, 30, 2026

20 people who take Ambien and Menest together, and have interactions are studied.

Ambien and Menest drug interactions.

What are the common drug interactions of Ambien and Menest, by gender? *:

female:

  1. Acne (skin problems that cause pimples)
  2. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  3. Pruritus (severe itching of the skin)
  4. Scab (a hard coating on the skin formed during the wound healing)
  5. Urinary tract infection
  6. Aortic valve incompetence
  7. Arrhythmia (irregular heartbeat)
  8. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  9. Balance disorder
  10. Bilirubinuria (presence of bilirubin in urine)

male:

n/a

What are the common drug interactions of Ambien and Menest, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Blood cholesterol increased
  2. Diabetes mellitus inadequate control
  3. Dysgeusia (disorder of the sense of taste)
  4. Hyperlipidaemia (presence of excess lipids in the blood)
  5. Obesity (having too much body fat)
  6. Type 1 diabetes mellitus
  7. Vomiting

40-49:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Type 2 diabetes mellitus
  3. Affective disorder (mental disorder)
  4. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  5. Aura
  6. Bipolar ii disorder (characterized by at least one episode of hypomania and at least one episode of major depression)
  7. Blood cholesterol increased
  8. Blood triglycerides increased
  9. Confusional state
  10. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

50-59:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  3. Hyperhidrosis (abnormally increased sweating)
  4. Neuropathy peripheral (surface nerve damage)
  5. Pancreatitis (inflammation of pancreas)

60+:

  1. Acne (skin problems that cause pimples)
  2. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  3. Aortic valve incompetence
  4. Arrhythmia (irregular heartbeat)
  5. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  6. Balance disorder
  7. Bilirubinuria (presence of bilirubin in urine)
  8. Blood pressure inadequately controlled
  9. Cardiac arrest
  10. Cardiac flutter (abnormal heart rhythm)

What are the existing conditions these people have? *

  1. Feeling Abnormal: 4 people, 20.00%
  2. Stress And Anxiety: 2 people, 10.00%
  3. Bipolar Disorder (mood disorder): 2 people, 10.00%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 10.00%
  5. Depression: 2 people, 10.00%
  6. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 10.00%
  7. High Blood Cholesterol: 2 people, 10.00%
  8. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 10.00%
  9. Muscle Spasms (muscle contraction): 2 people, 10.00%
  10. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Ambien and Menest?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ambien and Menest:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ambien:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Menest:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ambien and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Menest and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate and estrogens, esterified (the active ingredients of Ambien and Menest, respectively), and Ambien and Menest (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: