Ambien and Pulmicort flexhaler drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ambien (zolpidem tartrate) and Pulmicort flexhaler (budesonide). Common drug interactions include cellulitis staphylococcal among females and deafness among males.
The phase IV clinical study analyzes what interactions people have when they take Ambien and Pulmicort flexhaler. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.
What is Ambien?
Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.
What is Pulmicort flexhaler?
Pulmicort flexhaler has active ingredients of budesonide. It is often used in asthma. eHealthMe is studying from 5,527 Pulmicort flexhaler users. Check the latest studies of Pulmicort flexhaler.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
36 people who take Ambien and Pulmicort flexhaler together, and have interactions are studied.

What are the common drug interactions of Ambien and Pulmicort Flexhaler, by gender? *:
female:
- Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Headache (pain in head)
- Injection site haemorrhage (bleeding from injection site)
- Memory impairment
- Oedema peripheral (superficial swelling)
- Pain in extremity
- Renal failure (kidney dysfunction)
- Septic shock (shock due to blood infection)
- Anxiety
male:
- Deafness
- Dyspnoea (difficult or laboured respiration)
- Oxygen saturation decreased
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Headache (pain in head)
- Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
- Abdominal discomfort
- Blood creatinine increased
- Compression fracture (fracture due to pressure caused by injury)
- Decreased appetite
What are the common drug interactions of Ambien and Pulmicort Flexhaler, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Dyspepsia (indigestion)
- Maternal exposure during pregnancy (use of substance during pregnancy)
- Nephrolithiasis (calculi in the kidneys)
- Speech disorder
- Visual impairment
40-49:
- Dyspnoea (difficult or laboured respiration)
- Deafness
- Limb discomfort (discomfort in leg)
- Respiratory rate increased (excess breathing rate/min)
- Suffocation feeling
- Vertigo
- Wound infection
- Headache (pain in head)
- Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
- Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)
50-59:
- Gait disturbance
- Hand deformity
- Hyperkeratosis (thickening of the outer layer of the skin)
- Hypertension (high blood pressure)
- Injection site pain
- Injection site pruritus (severe itching at injection site)
- Injection site reaction
- Injection site swelling
- Joint destruction (joint damage)
- Open wound
60+:
- Back pain
- Fatigue (feeling of tiredness)
- Metapneumovirus infection (infection with human metapneumovirus)
- Pneumonia
- Pyelonephritis (inflammation of kidney caused by bacteria)
- Urinary tract infection
- Viral infection
- Anaemia (lack of blood)
- Breast cancer
- Drug hypersensitivity
What are the existing conditions these people have? *
- Pain: 8 people, 22.22%
- Sleep Disorder: 7 people, 19.44%
- High Blood Pressure: 7 people, 19.44%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 16.67%
- Stress And Anxiety: 5 people, 13.89%
- Immunodeficiency Common Variable: 5 people, 13.89%
- Hypersensitivity: 4 people, 11.11%
- Migraine (headache): 4 people, 11.11%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 11.11%
- High Blood Cholesterol: 4 people, 11.11%
* Approximation only. Some reports may have incomplete information.
Do you take Ambien and Pulmicort flexhaler?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Ambien (93,519 reports)
- Pulmicort flexhaler (5,527 reports)
Browse all drug interactions of Ambien and Pulmicort flexhaler:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ambien:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pulmicort flexhaler:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ambien and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pulmicort flexhaler and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on zolpidem tartrate and budesonide (the active ingredients of Ambien and Pulmicort flexhaler, respectively), and Ambien and Pulmicort flexhaler (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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