Ambien and Topicort drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ambien (zolpidem tartrate) and Topicort (desoximetasone). Common drug interactions include urinary tract infection among females and malignant pleural effusion among males.

The phase IV clinical study analyzes what interactions people have when they take Ambien and Topicort. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

What is Topicort?

Topicort has active ingredients of desoximetasone. eHealthMe is studying from 3,423 Topicort users. Check the latest studies of Topicort.



On Aug, 07, 2026

25 people who take Ambien and Topicort together, and have interactions are studied.

Ambien and Topicort drug interactions.

What are the common drug interactions of Ambien and Topicort, by gender? *:

female:

  1. Urinary tract infection
  2. Depression
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Sinusitis (inflammation of sinus)
  5. Alopecia (absence of hair from areas of the body)
  6. Arthralgia (joint pain)
  7. Bone pain
  8. Cellulitis (infection under the skin)
  9. Chest pain
  10. Dysphagia (a condition in which swallowing is difficult or painful)

male:

  1. Malignant pleural effusion (a condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue lining of lung)
  2. Plasmacytoma (neoplasm of plasma cells (usually in bone marrow))
  3. Swollen tongue (swelling of tongue)
  4. Angioedema (rapid swelling of the dermis)
  5. Ankle fracture
  6. Dyspnoea (difficult or laboured respiration)
  7. Fall
  8. Hyperhidrosis (abnormally increased sweating)
  9. Limb injury
  10. Pallor

What are the common drug interactions of Ambien and Topicort, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Abdominal pain upper
  2. Asthenia (weakness)
  3. Blood glucose increased
  4. Cholecystitis chronic (long lasting infection of gallbladder)
  5. Diarrhoea
  6. Gallbladder disorder
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  9. Nausea (feeling of having an urge to vomit)
  10. Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)

30-39:

n/a

40-49:

  1. Depression
  2. Sinusitis (inflammation of sinus)
  3. Alopecia (absence of hair from areas of the body)
  4. Arthralgia (joint pain)
  5. Bone pain
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  7. Cellulitis (infection under the skin)
  8. Chest pain
  9. Dysphagia (a condition in which swallowing is difficult or painful)
  10. General physical health deterioration (weak health status)

50-59:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  4. Drug intolerance (drug sensitivity)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Transaminases increased

60+:

  1. Death
  2. Malignant pleural effusion (a condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue lining of lung)
  3. Pallor
  4. Pleural effusion (water on the lungs)
  5. Pulse absent
  6. Sepsis syndrome (a clinical condition of blood infection)
  7. Swollen tongue (swelling of tongue)
  8. Thrombocytopenia (decrease of platelets in blood)
  9. Urinary tract infection
  10. Plasmacytoma (neoplasm of plasma cells (usually in bone marrow))

What are the existing conditions these people have? *

  1. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 11 people, 44.00%
  2. Pain: 9 people, 36.00%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 20.00%
  4. Nausea (feeling of having an urge to vomit): 4 people, 16.00%
  5. Stress And Anxiety: 3 people, 12.00%
  6. Constipation: 3 people, 12.00%
  7. Sleep Disorder: 3 people, 12.00%
  8. High Blood Pressure: 3 people, 12.00%
  9. Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 8.00%
  10. Anaemia (lack of blood): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ambien and Topicort:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ambien:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Topicort:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ambien and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Topicort and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate and desoximetasone (the active ingredients of Ambien and Topicort, respectively), and Ambien and Topicort (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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