Ambisome and Daptomycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ambisome (amphotericin b) and Daptomycin (daptomycin). Common drug interactions include septic shock among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Ambisome and Daptomycin. It is created by eHealthMe based on reports of 96 people who take the same drugs from the FDA, and is updated regularly.

What is Ambisome?

Ambisome has active ingredients of amphotericin b. eHealthMe is studying from 7,934 Ambisome users. Check the latest studies of Ambisome.

What is Daptomycin?

Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.

On Jul, 14, 2026

96 people who take Ambisome and Daptomycin together, and have interactions are studied.

Ambisome and Daptomycin drug interactions.

What are the common drug interactions of Ambisome and Daptomycin, by gender? *:

female:

Septic shock (shock due to blood infection)
Skin necrosis (skin damage)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Thrombocytopenia (decrease of platelets in blood)
Urinary tract infection
Abdominal infection
Abdominal pain
Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)

male:

Anaemia (lack of blood)
Oedema (fluid collection in tissue)
Cor pulmonale (enlargement of the right ventricle of the heart)
Left ventricular dysfunction
Myocarditis (inflammation of heart muscle myocardium)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Thrombocytopenia (decrease of platelets in blood)
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Cardiomyopathy (weakening of the heart muscle)
Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))

What are the common drug interactions of Ambisome and Daptomycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Cor pulmonale (enlargement of the right ventricle of the heart)
Left ventricular dysfunction
Myocarditis (inflammation of heart muscle myocardium)
Cardiomyopathy (weakening of the heart muscle)
Ejection fraction decreased (systolic heart failure)
Electrocardiogram qt prolonged
Enterococcal sepsis
Respiratory rate increased (excess breathing rate/min)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Brain natriuretic peptide increased

10-19:

Anticonvulsant drug level below therapeutic
Blood bicarbonate decreased
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cerebral toxoplasmosis (parasitic disease of brain caused by the protozoan toxoplasma gondii)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Diabetes insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function)
Disease progression
Drug resistance (reduction in effectiveness of a drug)
Glycosuria (excretion of glucose into the urine)

20-29:

Drug ineffective
Alopecia (absence of hair from areas of the body)
Ataxia (loss of full control of bodily movements)
Dizziness
Flushing (the warm, red condition of human skin)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Pyrexia (fever)

30-39:

Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Cardiac failure congestive
Death
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Febrile neutropenia (fever with reduced white blood cells)
Multi-organ failure (multisystem organ failure)
Renal impairment (severely reduced kidney function)
Sepsis (a severe blood infection that can lead to organ failure and death)
Alanine aminotransferase increased
Aspartate aminotransferase increased

40-49:

Respiratory failure (inadequate gas exchange by the respiratory system)
Skin necrosis (skin damage)
Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
Cardiomyopathy (weakening of the heart muscle)
Cellulitis (infection under the skin)
Coagulopathy (blood's ability to clot is impaired)
Complications of transplanted lung
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Ejection fraction decreased (systolic heart failure)

50-59:

Anaemia (lack of blood)
Oedema (fluid collection in tissue)
Systemic candida (whole body fungal infection)
Respiratory gas exchange disorder (gas exchange disease of respiratory system)
Renal failure (kidney dysfunction)
Hypercapnia (too much smoke)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Liver abscess (pus in liver)
Enterobacter sepsis (sepsis due to bacteria of the family enterobacteriaceae)
Blood disorder

60+:

Drug ineffective
Lichenoid keratosis (a skin disorder described by rapid growing, reddish to brown, benign (noncancerous) lesion on the skin)
Oral infection
Thrombocytopenia (decrease of platelets in blood)
Pathogen resistance
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Alanine aminotransferase increased
Ascites (accumulation of fluid in the abdominal cavity)
Atelectasis (partial or complete collapse of the lung)
Blood alkaline phosphatase increased

What are the existing conditions these people have? *

Fungal Infection: 21 people, 21.88%
Pyogenic Liver Abscess (liver abscess caused by bacteria): 18 people, 18.75%
Peritoneal Disorder: 16 people, 16.67%
Pain: 11 people, 11.46%
Sepsis (a severe blood infection that can lead to organ failure and death): 10 people, 10.42%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 8 people, 8.33%
Febrile Neutropenia (fever with reduced white blood cells): 7 people, 7.29%
Arthritis Infective (purulent invasion of a joint by an infectious agent which produces arthritis): 7 people, 7.29%
Mucormycosis (a rare infection caused by organisms that belong to a group of fungi called mucoromycotina): 6 people, 6.25%
Infection: 6 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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