Ambisome and Versed drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ambisome (amphotericin b) and Versed (midazolam hydrochloride). Common drug interactions include application site reaction among females and haematocrit decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Ambisome and Versed. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Ambisome?

Ambisome has active ingredients of amphotericin b. eHealthMe is studying from 7,934 Ambisome users. Check the latest studies of Ambisome.

What is Versed?

Versed has active ingredients of midazolam hydrochloride. It is often used in sedation during medical procedure. eHealthMe is studying from 6,869 Versed users. Check the latest studies of Versed.

On Jul, 15, 2026

18 people who take Ambisome and Versed together, and have interactions are studied.

What are the common drug interactions of Ambisome and Versed, by gender? *:

female:

Application site reaction
Ascites (accumulation of fluid in the abdominal cavity)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Back pain
Bacteraemia (presence of bacteria in the blood)
Blood magnesium decreased
Blood potassium increased
Bradyarrhythmia (heart slowness)
Budd chiari syndrome (problem that results from blood clotting in the veins flowing out of the liver (hepatic veins))

male:

Haematocrit decreased
Hypertension (high blood pressure)
Abdominal infection
Activated partial thromboplastin time prolonged
Ammonia decreased
Anion gap increased
Ascites (accumulation of fluid in the abdominal cavity)
Blast cell count increased
Blood albumin decreased
Blood calcium decreased

What are the common drug interactions of Ambisome and Versed, by age (0-1 to 60+)? *:

0-1:

Tachypnoea (a condition of rapid breathing over 20 per minute)
White blood cell count decreased
Abdominal infection
Activated partial thromboplastin time prolonged
Alanine aminotransferase increased
Ammonia decreased
Anaemia (lack of blood)
Anion gap increased
Aspartate aminotransferase increased
Blast cell count increased

2-9:

Anaemia (lack of blood)
Delayed engraftment
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)

10-19:

Aspergillosis (an infection caused by a fungus called aspergillus)
Multi-organ failure (multisystem organ failure)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pleural effusion (water on the lungs)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Skin lesion

20-29:

n/a

30-39:

n/a

40-49:

Thrombocytopenia (decrease of platelets in blood)

50-59:

Ascites (accumulation of fluid in the abdominal cavity)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Death
Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
Fluid overload (too much fluid in the blood)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematocrit decreased
Haemoglobin decreased
Hyperglycaemia (high blood sugar)
Hypertension (high blood pressure)

60+:

Budd chiari syndrome (problem that results from blood clotting in the veins flowing out of the liver (hepatic veins))
Pneumonia
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Pleural effusion (water on the lungs)
Pneumonia fungal
Rectal bleeding (bleeding from rectum)
Sepsis (a severe blood infection that can lead to organ failure and death)
Respiratory distress (difficulty in breathing)
Abdominal pain
Blood culture positive

What are the existing conditions these people have? *

Sedation: 5 people, 27.78%
Nausea (feeling of having an urge to vomit): 5 people, 27.78%
Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 22.22%
Cryptococcosis (potentially fatal fungal disease): 4 people, 22.22%
Asthma: 4 people, 22.22%
Hiv Infection: 4 people, 22.22%
Ill-Defined Disorder: 2 people, 11.11%
Diabetes: 2 people, 11.11%
Acute Leukaemia (blood cancer): 1 person, 5.56%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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