Amitiza and Flovent drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amitiza (lubiprostone) and Flovent (fluticasone propionate). Common drug interactions include dry skin among females and upper respiratory tract infection among males.

The phase IV clinical study analyzes what interactions people have when they take Amitiza and Flovent. It is created by eHealthMe based on reports of 88 people who take the same drugs from the FDA, and is updated regularly.

What is Amitiza?

Amitiza has active ingredients of lubiprostone. It is often used in constipation. eHealthMe is studying from 10,567 Amitiza users. Check the latest studies of Amitiza.

What is Flovent?

Flovent has active ingredients of fluticasone propionate. It is often used in asthma. eHealthMe is studying from 44,817 Flovent users. Check the latest studies of Flovent.

On Aug, 07, 2026

88 people who take Amitiza and Flovent together, and have interactions are studied.

What are the common drug interactions of Amitiza and Flovent, by gender? *:

female:

Dry skin
Emotional distress
Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
Hyperacusis (disorder in loudness perception)
Hypertension (high blood pressure)
Injection site pain
Meniere's disease (a disorder of the inner ear that can affect hearing and balance to a varying degree)
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)

male:

Upper respiratory tract infection
Chronic kidney disease
Blood pressure systolic decreased
Bone density decreased
Bowel movement irregularity
Complex partial seizures (epileptic seizure)
Cough
Depression
Diarrhoea
Drug effect decreased

What are the common drug interactions of Amitiza and Flovent, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Hyperacusis (disorder in loudness perception)
Pneumonia
Upper respiratory tract infection
Cough
Influenza
Intestinal resection
Mood swings (an extreme or rapid change in mood)
Pulmonary function test decreased
Rhinorrhoea (watery mucus discharge from the nose)

10-19:

Dizziness
Alopecia (absence of hair from areas of the body)
Ankle fracture
Anxiety
Blood glucose decreased
Chest discomfort
Cough
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Hunger

20-29:

Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Blood pressure fluctuation
Chest discomfort
Death
Dizziness
Headache (pain in head)
Heart rate decreased
Nausea (feeling of having an urge to vomit)
Palpitations (feelings or sensations that your heart is pounding or racing)

30-39:

Drug ineffective
Borderline personality disorder
Chronic kidney disease
Meniere's disease (a disorder of the inner ear that can affect hearing and balance to a varying degree)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Therapeutic response unexpected

40-49:

Subcutaneous abscess
Fatigue (feeling of tiredness)
Headache (pain in head)
Arthralgia (joint pain)
Back pain
Blood pressure decreased
Chronic kidney disease
Cystitis (inflammation of the wall of the bladder)
Disturbance in attention
Dizziness

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Muscle spasms (muscle contraction)
Renal injury (kidney injury)
Abdominal pain upper
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Depression
Emotional distress

60+:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Arrhythmia (irregular heartbeat)
Blood pressure systolic decreased
Blood triglycerides increased
Bowel movement irregularity
Cardiac failure congestive
Cardiovascular disorder (heart diseases)
Complex partial seizures (epileptic seizure)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

What are the existing conditions these people have? *

Cystic Fibrosis (disease of the secretary glands): 21 people, 23.86%
Pain: 19 people, 21.59%
High Blood Pressure: 18 people, 20.45%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 18 people, 20.45%
High Blood Cholesterol: 15 people, 17.05%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 13.64%
Depression: 11 people, 12.50%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 11.36%
Stress And Anxiety: 9 people, 10.23%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 7.95%

* Approximation only. Some reports may have incomplete information.

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