Amitiza and Mircera drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amitiza (lubiprostone) and Mircera (methoxy polyethylene glycol-epoetin beta). Common drug interactions include abdominal distension among females and cardiac failure among males.

The phase IV clinical study analyzes what interactions people have when they take Amitiza and Mircera. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Amitiza?

Amitiza has active ingredients of lubiprostone. It is often used in constipation. eHealthMe is studying from 10,567 Amitiza users. Check the latest studies of Amitiza.

What is Mircera?

Mircera has active ingredients of methoxy polyethylene glycol-epoetin beta. eHealthMe is studying from 10,321 Mircera users. Check the latest studies of Mircera.

On Jul, 26, 2026

17 people who take Amitiza and Mircera together, and have interactions are studied.

What are the common drug interactions of Amitiza and Mircera, by gender? *:

female:

Abdominal distension
Anaemia (lack of blood)
Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
Blood zinc decreased
Cardiac murmur (an heart sound in valve abnormality)
Cardiomegaly (increased size of heart than normal)
Fluid overload (too much fluid in the blood)
Generalised oedema (swelling all over the body)
Haemoglobin decreased
Hyperchloraemia (an excess of chlorides in the blood)

male:

Cardiac failure
Altered state of consciousness (altered state of mind)
Memory impairment
Nausea (feeling of having an urge to vomit)
Renal impairment (severely reduced kidney function)
Somnolence (a state of near-sleep, a strong desire for sleep)
Tremor (trembling or shaking movements in one or more parts of your body)
Vision blurred
Anaemia (lack of blood)
Device related infection

What are the common drug interactions of Amitiza and Mircera, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Abdominal pain upper
Anaemia (lack of blood)
Device related infection
Dyspepsia (indigestion)
Faeces discoloured
Fall
Femoral neck fracture (neck of femur bone fracture)
Gastric ulcer (stomach ulcer)
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

60+:

Malaise (a feeling of general discomfort or uneasiness)
Cardiac failure
Headache (pain in head)
Memory impairment
Nausea (feeling of having an urge to vomit)
Renal impairment (severely reduced kidney function)
Somnolence (a state of near-sleep, a strong desire for sleep)
Tremor (trembling or shaking movements in one or more parts of your body)
Vision blurred
Abdominal distension

What are the existing conditions these people have? *

Nephrogenic Anaemia (anaemia due to kidney disease): 11 people, 64.71%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 4 people, 23.53%
Cardiac Failure Chronic: 4 people, 23.53%
High Blood Cholesterol: 3 people, 17.65%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 17.65%
Oedema Due To Renal Disease (fluid collection in tissue due to kidney disease): 3 people, 17.65%
Nephritis (inflammation of the nephrons in the kidneys): 3 people, 17.65%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 17.65%
Iron Deficiency Anaemia: 3 people, 17.65%
Insomnia (sleeplessness): 3 people, 17.65%

* Approximation only. Some reports may have incomplete information.

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