Amitriptyline hydrochloride and Halcion drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amitriptyline hydrochloride (amitriptyline hydrochloride) and Halcion (triazolam). Common drug interactions include pain in extremity among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Amitriptyline hydrochloride and Halcion. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Amitriptyline hydrochloride?

Amitriptyline hydrochloride has active ingredients of amitriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 20,054 Amitriptyline hydrochloride users. Check the latest studies of Amitriptyline hydrochloride.

What is Halcion?

Halcion has active ingredients of triazolam. It is often used in insomnia. eHealthMe is studying from 8,268 Halcion users. Check the latest studies of Halcion.



On Jul, 16, 2026

20 people who take Amitriptyline hydrochloride and Halcion together, and have interactions are studied.

Amitriptyline hydrochloride and Halcion drug interactions.

What are the common drug interactions of Amitriptyline Hydrochloride and Halcion, by gender? *:

female:

  1. Pain in extremity
  2. Pain in jaw
  3. Peripheral swelling
  4. Proctalgia (pain in the rectum)
  5. Pruritus (severe itching of the skin)
  6. Pyelonephritis (inflammation of kidney caused by bacteria)
  7. Pyrexia (fever)
  8. Rectal haemorrhage (bleeding from anus)
  9. Red blood cell count decreased
  10. Renal disorder (kidney disease)

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Hyperkeratosis (thickening of the outer layer of the skin)
  3. Gait disturbance
  4. Gastritis haemorrhagic (inflammation of stomach with bleeding)
  5. Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Pneumonia
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Skin disorder (skin disease)
  10. Staphylococcal infection (an infection with staphylococcus bacteria)

What are the common drug interactions of Amitriptyline Hydrochloride and Halcion, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Drug abuse

40-49:

  1. Drug toxicity
  2. Coma (state of unconsciousness lasting more than six hours)
  3. Overdose
  4. Altered state of consciousness (altered state of mind)
  5. Blood alkaline phosphatase increased
  6. Blood pressure diastolic decreased
  7. Blood pressure systolic increased
  8. Depressed level of consciousness
  9. Fall
  10. Gamma-glutamyltransferase increased

50-59:

  1. Pneumonia
  2. Pruritus (severe itching of the skin)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Skin disorder (skin disease)
  5. Staphylococcal infection (an infection with staphylococcus bacteria)
  6. Venous occlusion (the blocking of venous return)
  7. Wound infection staphylococcal
  8. Pyrexia (fever)
  9. Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases)
  10. Bradyphrenia (neurological term referring to the slowness of thought common to many disorders of the brain)

60+:

  1. Drug abuse
  2. Confusional state
  3. Aphasia (damage to the parts of the brain that control language)
  4. Arthralgia (joint pain)
  5. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  6. Back pain
  7. Bone disorder
  8. Cellulitis (infection under the skin)
  9. Cerebral infarction (less blood supply to brain resulting tissue damage)
  10. Coma (state of unconsciousness lasting more than six hours)

What are the existing conditions these people have? *

  1. Diabetes: 3 people, 15.00%
  2. Pain: 2 people, 10.00%
  3. Asthma: 2 people, 10.00%
  4. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 1 person, 5.00%
  5. Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 5.00%
  6. Intentional Self-Injury: 1 person, 5.00%
  7. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 1 person, 5.00%
  8. Colon Cancer: 1 person, 5.00%
  9. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Amitriptyline hydrochloride and Halcion:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amitriptyline hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Halcion:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amitriptyline hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Halcion and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on amitriptyline hydrochloride and triazolam (the active ingredients of Amitriptyline hydrochloride and Halcion, respectively), and Amitriptyline hydrochloride and Halcion (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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